Claims for Patent: 10,023,654

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Summary for Patent: 10,023,654

Title:	Anti-PCSK9 antibodies
Abstract:	An human antibody or antigen-binding fragment of a human antibody that specifically binds and inhibits human proprotein convertase subtilisin/kexin type 9 (hPCSK9) characterized by the ability to reduce serum LDL cholesterol by 40-80% over a 24, 60 or 90 day period relative to predose levels, with little or no reduction in serum HDL cholesterol and/or with little or no measurable effect on liver function, as determined by ALT and AST measurements.
Inventor(s):	Sleeman Mark W., Martin Joel H., Huang Tammy T., MacDonald Douglas
Assignee:	Regeneron Pharmaceuticals, Inc.
Application Number:	US15377364

Details for Patent 10,023,654

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Regeneron Pharmaceuticals, Inc.	PRALUENT	alirocumab	Injection	125559	July 24, 2015	⤷ Subscribe	2036-12-13
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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