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Last Updated: December 27, 2024

Claims for Patent: 10,206,894


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Summary for Patent: 10,206,894
Title:Compounds for use in treatment of mucositis
Abstract: The present invention provides methods for treating and/or preventing mucositis with one or more compounds, or pharmaceutically acceptable salts thereof, disclosed herein, or compositions comprising the same.
Inventor(s): Scott; Richard W. (Radnor, PA), Korczak; Bozena (Wayne, PA)
Assignee: Innovation Pharmaceuticals Inc. (Beverly, MA)
Application Number:15/702,186
Patent Claims:1. An oral, buccal, or sublingual pharmaceutical composition comprising a compound of the formula ##STR00549## or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, wherein the compound is present at 1 mg/ml, 3 mg/ml, or 10 mg/ml.

2. The pharmaceutical composition of claim 1, wherein the pharmaceutical composition is a liquid.

3. The pharmaceutical composition of claim 1, wherein the pharmaceutical composition is a rinse.

4. The pharmaceutical composition of claim 1, wherein the compound is present at 1 mg/ml.

5. The pharmaceutical composition of claim 1, wherein the compound is present at 3 mg/ml.

6. The pharmaceutical composition of claim 1, wherein the compound is present at 10 mg/ml.

7. The pharmaceutical composition of claim 1, further comprising an analgesic.

8. The pharmaceutical composition of claim 1, further comprising an antibiotic.

9. The pharmaceutical composition of claim 1, further comprising palifermin.

10. The pharmaceutical composition of claim 1, wherein the pharmaceutical composition is an oral pharmaceutical composition.

11. The pharmaceutical composition of claim 1, wherein the pharmaceutical composition is a buccal pharmaceutical composition.

12. The pharmaceutical composition of claim 1, wherein the pharmaceutical composition is a sublingual pharmaceutical composition.

13. An oral, buccal, or sublingual pharmaceutical composition comprising a compound of the formula ##STR00550## or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, and further comprising palifermin.

14. The pharmaceutical composition of claim 13, wherein the pharmaceutical composition is a liquid.

15. The pharmaceutical composition of claim 13, wherein the pharmaceutical composition is a rinse.

16. The pharmaceutical composition of claim 13, wherein the compound is present at 1 mg/ml.

17. The pharmaceutical composition of claim 13, wherein the compound is present at 3 mg/ml.

18. The pharmaceutical composition of claim 13, wherein the compound is present at 10 mg/ml.

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