Claims for Patent: 10,286,058

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Summary for Patent: 10,286,058

Title:	Vaccines against HPV and HPV-related diseases
Abstract:	Embodiments relate to novel vaccines against human papillomavirus (HPV) and HPV-related diseases, including multiple types of cancers. The HPV vaccines are composed of anti-human dendritic cell (DC) surface receptor antibodies, including CD40, and E6/7 proteins of HPV 16 and 18. The technology described is not limited to making vaccines against HPV16- and HPV18-related diseases and can be applied to making vaccines carrying E6/7 from any type of HPV. The HPV vaccines described can target DCs, major and professional antigen presenting cells (APCs), and can induce and activate potent HPV E6/7-specific and strong CD4+ and CD8+ T cell responses. The HPV vaccines can be used for the prevention of HPV infection and HPV-related diseases as well as for the treatment of HPV-related diseases, including cancers.
Inventor(s):	Oh SangKon, Zurawski Sandra, Zurawski Gerard
Assignee:	Baylor Research Institute
Application Number:	US15111357
Patent Claims:

Details for Patent 10,286,058

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Merck Sharp & Dohme Llc	GARDASIL	human papillomavirus quadrivalent (types 6, 11, 16 and 18) vaccine, recombinant	Injection	125126	June 08, 2006	10,286,058	2035-01-13
Glaxosmithkline Biologicals	CERVARIX	human papillomavirus bivalent (types 16 and 18) vaccine, recombinant	Injection	125259	October 16, 2009	10,286,058	2035-01-13
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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