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Last Updated: April 6, 2025

Claims for Patent: 10,336,983


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Summary for Patent: 10,336,983
Title:Method for increasing the specific production rate of eukaryotic cells
Abstract:The current invention reports the use of meta-tyrosine for increasing the specific productivity of a eukaryotic cell that produces/expresses a polypeptide. In the current method it is not necessary to perform a temperature-, osmolality- or pH shift or to add drugs like valproic acid or sodium butyrate to modulate the specific productivity of the cultivated cells. The method does not affect cell viability or product titer.
Inventor(s):Popp Oliver
Assignee:Hoffmann-La Roche Inc.
Application Number:US15428279

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