Claims for Patent: 10,888,611

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Summary for Patent: 10,888,611

Title:	Neisseria meningitidis
Abstract:	In one aspect, the invention relates to a composition including a first polypeptide having the sequence set forth in SEQ ID NO: 1 and a second polypeptide having the sequence set forth in SEQ ID NO: 2. In one embodiment, the composition includes about 120 μg/ml of a first polypeptide including the amino acid sequence set forth in SEQ ID NO: 1, 120 μg/ml of a second polypeptide including the amino acid sequence set forth in SEQ ID NO: 2, about 2.8 molar ratio polysorbate-80 to the first polypeptide, about 2.8 molar ratio polysorbate-80 to the second polypeptide, about 0.5 mg/ml aluminum, about 10 mM histidine, and about 150 mM sodium chloride. In one embodiment, a dose of the composition is about 0.5 ml in total volume. In one embodiment, two-doses of the composition induce a bactericidal titer against diverse heterologous subfamily A and subfamily B strains in a human.
Inventor(s):	Jansen Kathrin Ute, Anderson Annaliesa Sybil, Arumugham Rasappa Gounder, Farley John Erwin, Fletcher Leah Diane, Harris Shannon Lea, Jones Thomas Richard, Khandke Lakshmi, Loun Bounthon, Perez John Lance, Zlotnick Gary Warren
Assignee:	PFIZER INC.
Application Number:	US15543232
Patent Claims:

Details for Patent 10,888,611

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Merck Sharp & Dohme Llc	GARDASIL	human papillomavirus quadrivalent (types 6, 11, 16 and 18) vaccine, recombinant	Injection	125126	June 08, 2006	⤷ Subscribe	2036-02-16
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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