Claims for Patent: 5,814,605

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Summary for Patent: 5,814,605

Title:	Therapeutic uses of keratinocyte growth factor
Abstract:	Based on extensive in vivo studies in animals, it has now been discovered that KGF stimulates proliferation, growth and differentiation in various cells of epithelial tissue, besides keratinocytes. This better understanding of the biological effects of KGF in vivo enables the use of this polypeptide as a therapeutic agent, suitably formulated in a pharmaceutical composition, for the specific treatment of disease states and medical conditions afflicting tissues and organs such as the dermal adnexae, the liver, the lung, and the gastrointestinal tract.
Inventor(s):	Pierce; Glenn Francis (Rancho Santa Fe, CA), Housley; Regina Mae (Thousand Oaks, CA), Morris; Charles Frederick (Newbury Park, CA)
Assignee:	Amgen Inc. (Thousand Oaks, CA)
Application Number:	08/484,065
Patent Claims:	1. A pharmaceutical composition comprising a therapeutically effective amount of a keratinocyte growth factor product and a non-aqueous carrier. 2. The pharmaceutical composition of claim 1, wherein the non-aqueous carrier is selected from the group consisting of collagen, hyaluronic acid and carboxymethylcellulose. 3. The pharmaceutical composition of claim 1, wherein the keratinocyte growth factor product is recombinantly produced keratinocyte growth factor. 4. The pharmaceutical composition of claim 3, wherein the recombinantly produced keratinocyte growth factor is produced in bacterial cells. 5. The pharmaceutical composition of claim 4, wherein the bacterial cells are E. coli.

Details for Patent 5,814,605

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Swedish Orphan Biovitrum Ab (publ)	KEPIVANCE	palifermin	For Injection	125103	December 15, 2004	⤷ Subscribe	2015-09-29
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 5,814,605

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Country	Patent Number	Estimated Expiration
World Intellectual Property Organization (WIPO)	9423032	⤷ Subscribe
United States of America	5965530	⤷ Subscribe
United States of America	5824643	⤷ Subscribe
Ukraine	46706	⤷ Subscribe
Slovakia	281674	⤷ Subscribe
>Country	>Patent Number	>Estimated Expiration

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