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Last Updated: December 24, 2024

Claims for Patent: 5,908,621


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Summary for Patent: 5,908,621
Title: Polyethylene glycol modified interferon therapy
Abstract:A method comprising administering a PEG.sub.12000 -IFN alpha conjugate to an individual afflicted with a viral infection susceptible of treatment with interferon alpha, preferably chronic hepatitis C, is disclosed.
Inventor(s): Glue; Paul (Flemington, NJ), Cutler; David L. (Morristown, NJ), Affrime; Melton B. (Flemington, NJ)
Assignee: Schering Corporation (Kenilworth, NJ)
Application Number:08/839,101
Patent Claims:1. A method of treating hepatitis C viral infections in mammals which comprises administering PEG.sub.12000 -interferon alpha-2b in an amount of 0.5-2.0 .mu.g/kg in one or two doses per week to mammals in need of such treating.

2. A method of treating hepatitis C viral infections in mammals which comprises administering PEG.sub.12000 -interferon alpha-2b in an amount of 0.5 .mu.g/kg twice per week to mammals in need of such treating.

3. A method of treating hepatitis C viral infections in mammals which comprises administering PEG.sub.12000 -interferon alpha-2b in an amount of 2.0 .mu.g/kg once per week to mammals in need of such treating.

4. A method of treating hepatitis C viral infections in mammals which comprises administering PEG.sub.12000 -interferon alpha-2b in an amount of 0.5, 1.0 or 1.5 .mu.g/kg once per week to mammals in need of such treating .

Details for Patent 5,908,621

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Merck Sharp & Dohme Llc PEGINTRON peginterferon alfa-2b Injection 103949 January 19, 2001 5,908,621 2015-11-02
Merck Sharp & Dohme Llc SYLATRON peginterferon alfa-2b For Injection 103949 March 29, 2011 5,908,621 2015-11-02
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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