Claims for Patent: 5,908,621
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Summary for Patent: 5,908,621
Title: | Polyethylene glycol modified interferon therapy |
Abstract: | A method comprising administering a PEG.sub.12000 -IFN alpha conjugate to an individual afflicted with a viral infection susceptible of treatment with interferon alpha, preferably chronic hepatitis C, is disclosed. |
Inventor(s): | Glue; Paul (Flemington, NJ), Cutler; David L. (Morristown, NJ), Affrime; Melton B. (Flemington, NJ) |
Assignee: | Schering Corporation (Kenilworth, NJ) |
Application Number: | 08/839,101 |
Patent Claims: | 1. A method of treating hepatitis C viral infections in mammals which comprises administering PEG.sub.12000 -interferon alpha-2b in an amount of 0.5-2.0 .mu.g/kg in one or two doses
per week to mammals in need of such treating.
2. A method of treating hepatitis C viral infections in mammals which comprises administering PEG.sub.12000 -interferon alpha-2b in an amount of 0.5 .mu.g/kg twice per week to mammals in need of such treating. 3. A method of treating hepatitis C viral infections in mammals which comprises administering PEG.sub.12000 -interferon alpha-2b in an amount of 2.0 .mu.g/kg once per week to mammals in need of such treating. 4. A method of treating hepatitis C viral infections in mammals which comprises administering PEG.sub.12000 -interferon alpha-2b in an amount of 0.5, 1.0 or 1.5 .mu.g/kg once per week to mammals in need of such treating . |
Details for Patent 5,908,621
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Merck Sharp & Dohme Llc | PEGINTRON | peginterferon alfa-2b | Injection | 103949 | January 19, 2001 | 5,908,621 | 2015-11-02 |
Merck Sharp & Dohme Llc | SYLATRON | peginterferon alfa-2b | For Injection | 103949 | March 29, 2011 | 5,908,621 | 2015-11-02 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |
International Patent Family for US Patent 5,908,621
Country | Patent Number | Estimated Expiration |
---|---|---|
South Africa | 983543 | ⤷ Subscribe |
World Intellectual Property Organization (WIPO) | 9848840 | ⤷ Subscribe |
World Intellectual Property Organization (WIPO) | 9716204 | ⤷ Subscribe |
>Country | >Patent Number | >Estimated Expiration |
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