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Last Updated: December 23, 2024

Claims for Patent: 6,572,852


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Summary for Patent: 6,572,852
Title: Method for suppressing inflammatory responses by administering TNFR
Abstract:Tumor necrosis factor receptor proteins, DNAs and expression vectors encoding TNF receptors, and processes for producing TNF receptors as products of recombinant cell culture, are disclosed.
Inventor(s): Smith; Craig A. (Seattle, WA), Goodwin; Raymond G. (Seattle, WA), Beckmann; M. Patricia (Poulsbo, WA)
Assignee: Immunex Corporation (Seattle, WA)
Application Number:09/758,124
Patent Claims:1. A method of suppressing a TNF-dependent inflammatory response in a mammal comprising administering an effective amount of recombinant tumor necrosis factor receptor (TNFR) to a mammal afflicted with said inflammatory response, wherein said recombinant TNFR comprises amino acids 1-163 of SEQ ID NO:2.

2. The method of claim 1, wherein said recombinant TNFR consists essentially of amino acids 1-163 of SEQ ID NO:2.

3. The method of claim 2, wherein said recombinant TNFR comprises amino acids 1-185 of SEQ ID NO:2.

4. The method of claim 3, wherein said recombinant TNFR comprises amino acids 1-235 of SEQ ID NO:2.

5. A method of suppressing a TNF-dependent inflammatory response in a mammal comprising administering an effective amount of tumor necrosis factor receptor (TNFR) to a mammal afflicted with said inflammatory response, wherein said TNFR comprises amino acids 1-163 of SEQ ID NO:2.

6. The method of claim 5, wherein said TNFR consists essentially of amino acids 1-163 of SEQ ID NO:2.

7. The method of claim 6, wherein said TNFR comprises amino acids 1-185 of SEQ ID NO:2.

8. The method of claim 7, wherein said TNFR comprises amino acids 1-235 of SEQ ID NO:2.

Details for Patent 6,572,852

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Immunex Corporation ENBREL etanercept For Injection 103795 November 02, 1998 ⤷  Subscribe 2009-09-05
Immunex Corporation ENBREL etanercept For Injection 103795 May 27, 1999 ⤷  Subscribe 2009-09-05
Immunex Corporation ENBREL etanercept Injection 103795 September 27, 2004 ⤷  Subscribe 2009-09-05
Immunex Corporation ENBREL etanercept Injection 103795 February 01, 2007 ⤷  Subscribe 2009-09-05
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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