Claims for Patent: 8,574,869
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Summary for Patent: 8,574,869
Title: | Prevention of disulfide bond reduction during recombinant production of polypeptides |
Abstract: | Provided herein are methods for preventing the reduction of disulfide bonds during the recombinant production of disulfide-containing polypeptides. In particular, the invention concerns the prevention of disulfide bond reduction during harvesting of disulfide-containing polypeptides, including antibodies, from recombinant host cell cultures. |
Inventor(s): | Kao Yung-Hsiang, Laird Michael W., Schmidt Melody Trexler, Wong Rita L., Hewitt Daniel P. |
Assignee: | Genentech, Inc. |
Application Number: | US13354223 |
Details for Patent 8,574,869
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Genentech, Inc. | AVASTIN | bevacizumab | Injection | 125085 | February 26, 2004 | ⤷ Try for Free | 2032-01-19 |
Genentech, Inc. | LUCENTIS | ranibizumab | Injection | 125156 | June 30, 2006 | ⤷ Try for Free | 2032-01-19 |
Genentech, Inc. | LUCENTIS | ranibizumab | Injection | 125156 | August 10, 2012 | ⤷ Try for Free | 2032-01-19 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |