Patent: 10,004,686

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Summary for Patent: 10,004,686

Scope and claims summary:

Title:	Lipid construct for delivery of insulin to a mammal
Abstract:	The instant invention is drawn to a hepatocyte targeted composition comprising insulin associated with a lipid construct comprising an amphipathic lipid and an extended amphipathic lipid that targets the construct to a receptor displayed by an hepatocyte. The composition can comprise a mixture of free insulin and insulin associated with the complex. The composition can be modified to protect insulin and the complex from degradation. The invention also includes methods for the manufacture of the composition and loading insulin into the composition and recycling various components of the composition. Methods of treating individuals inflicted with diabetes.
Inventor(s):	Lau; John R. (Howard, OH), Geho; W. Blair (Wooster, OH)
Assignee:	SDG, Inc. (Cleveland, OH)
Application Number:	13/916,115
Patent Claims:	see list of patent claims

Details for Patent 10,004,686

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Eli Lilly And Company	HUMULIN R U-100	insulin human	Injection	018780	October 28, 1982	10,004,686	2025-05-23
Eli Lilly And Company	HUMULIN R U-500	insulin human	Injection	018780	December 29, 2015	10,004,686	2025-05-23
Eli Lilly And Company	HUMULIN R U-100	insulin human	Injection	018780	August 06, 1998	10,004,686	2025-05-23
Eli Lilly And Company	HUMULIN R U-500	insulin human	Injection	018780	March 31, 1994	10,004,686	2025-05-23
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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