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Last Updated: December 23, 2024

Patent: 10,011,856


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Summary for Patent: 10,011,856
Title:Decreasing lactate level and increasing polypeptide production by downregulating the expression of lactate dehydrogenase and pyruvate dehydrogenase kinase
Abstract:The present invention provides methods and compositions for reducing lactate production and increasing polypeptide production in cultured cells. In one aspect, the invention provides a method comprising culturing cells expressing a) a small interfering RNA (siRNA) specific for a lactate dehydrogenase (LDH) and b) an siRNA specific for a pyruvate dehydrogenase kinase (PDHK). In another aspect, the invention provides cultured cells or vectors comprising an siRNA specific for a LDH and an siRNA specific for a PDHK.
Inventor(s):Zhou Meixia, Snedecor Bradley Richard, Ng Chi Kin Domingos, Shen Amy
Assignee:Genentech, Inc.
Application Number:US15268424
Patent Claims:see list of patent claims
Patent landscape, scope, and claims summary:

Analyzing the Claims and Patent Landscape of United States Patent 10,011,856

Introduction

Understanding the claims and patent landscape of a specific patent is crucial for businesses, researchers, and legal professionals. This analysis will delve into the details of United States Patent 10,011,856, examining its claims, the broader patent landscape, and the strategic insights that can be derived from this analysis.

Understanding the Patent

To begin, it is essential to understand the subject matter of the patent. However, since the specific details of U.S. Patent 10,011,856 are not provided in the sources, we will focus on a general approach to analyzing patents and their landscapes.

Claims Analysis

Claim Structure

Patent claims are the heart of any patent, defining the scope of the invention. Claims are typically categorized into independent and dependent claims. Independent claims stand alone and define the invention broadly, while dependent claims refer back to and further limit the independent claims[4].

Claim Interpretation

Interpreting the claims involves understanding the language and the scope of protection they offer. This includes identifying key terms, understanding the relationships between different claims, and determining the boundaries of what is considered novel and non-obvious.

Claim Validity

The validity of claims can be challenged through various means, including prior art searches, obviousness arguments, and inter partes review (IPR) proceedings. For example, in the context of IPR, challenges to patentability often overlap with joint invalidity contentions in district court litigation, as seen in the case of U.S. Patent 10,299,336 B2[2].

Patent Landscape Analysis

Definition and Importance

Patent landscape analysis is a comprehensive approach to understanding the patent environment surrounding a particular technology or invention. It goes beyond simple patentability searches by providing a high-level view of the entire technology area, helping businesses and R&D managers make strategic decisions[3].

Identifying Key Players

A patent landscape analysis helps identify key players in the field, including competitors and potential collaborators. By mapping patent portfolios, one can see which companies are heavily invested in specific technologies and where there might be opportunities for innovation or partnership.

Technology Saturation

Analyzing the patent landscape can reveal areas of high technology saturation, indicating mature technologies where further innovation might be challenging. This can prompt businesses to pivot towards newer, less saturated areas of innovation[3].

Time-Slicing and Trend Analysis

Time-slicing involves analyzing patent data over different time periods to identify trends and shifts in technological focus. This can help in understanding the evolution of technologies and the strategic directions of key players[3].

Tools and Resources for Patent Landscape Analysis

Patent Public Search

The USPTO's Patent Public Search tool is a powerful resource for conducting comprehensive patent searches. It offers enhanced access to prior art and improves the overall patent searching process[4].

Global Dossier

The Global Dossier service provides access to the file histories of related applications from participating IP Offices, allowing users to see the patent family for a specific application and track office actions and citations[4].

Common Citation Document (CCD)

The CCD application consolidates prior art cited by all participating offices for the family members of a patent application, enabling a single-point access to citation data and facilitating a more integrated global patent system[4].

Strategic Insights

Identifying Gaps and Opportunities

A thorough patent landscape analysis can uncover gaps in current technologies and identify opportunities for innovation. By analyzing what has been patented and what remains unexplored, businesses can make informed decisions about where to focus their R&D efforts[3].

Monitoring Competitors

Keeping an eye on the patent activities of competitors is crucial. This involves tracking their patent filings, identifying their areas of focus, and understanding their strategic directions. This information can help in developing competitive strategies and avoiding potential legal conflicts[3].

Licensing and Collaboration

Understanding the patent landscape can also facilitate licensing and collaboration opportunities. By identifying companies with complementary technologies, businesses can explore partnerships that drive innovation and reduce the risk of patent infringement[3].

Legal Considerations

Inter Partes Review (IPR)

IPR proceedings, such as those described in the context of U.S. Patent 10,299,336 B2, can significantly impact the validity of patent claims. Understanding the legal framework and the potential for IPR challenges is essential for maintaining the integrity of a patent portfolio[2].

Real Party in Interest

Determining the real party in interest is critical in IPR proceedings. This involves identifying whether the petitioner has a substantial interest in the outcome, often through control, funding, or substantial coordination with another party[2].

Case Study: Hypothetical Analysis of U.S. Patent 10,011,856

Hypothetical Claims

Assuming U.S. Patent 10,011,856 pertains to a novel method for improving biotechnological processes, the claims would likely include:

  • Independent claims defining the method broadly.
  • Dependent claims specifying particular steps or components of the method.

Patent Landscape

A patent landscape analysis might reveal:

  • Key players in the biotechnology sector with significant patent portfolios related to similar methods.
  • Areas of high technology saturation, indicating where further innovation might be challenging.
  • Trends in patent filings over time, showing shifts in technological focus.

Strategic Insights

  • Identifying gaps in current biotechnological processes that the patented method addresses.
  • Monitoring competitors' patent activities to understand their strategic directions.
  • Exploring licensing or collaboration opportunities with companies holding complementary patents.

Key Takeaways

  • Comprehensive Claims Analysis: Understanding the structure and scope of patent claims is crucial for determining the validity and enforceability of a patent.
  • Patent Landscape Analysis: This approach provides a high-level view of the technology area, helping businesses make strategic decisions about innovation and competition.
  • Legal Considerations: IPR proceedings and the identification of the real party in interest are critical for maintaining the integrity of a patent portfolio.
  • Strategic Insights: Identifying gaps, monitoring competitors, and exploring licensing opportunities are key to leveraging patent landscape analysis effectively.

FAQs

What is the purpose of a patent landscape analysis?

A patent landscape analysis helps businesses and R&D managers understand the broader patent environment, identify key players, and make strategic decisions about innovation and competition.

How do you identify key players in a patent landscape analysis?

Key players are identified by mapping their patent portfolios and analyzing their focus areas and trends in patent filings over time.

What is the difference between a basic patentability search and a full patent landscape analysis?

A basic patentability search looks for prior art directed to specific claims, while a full patent landscape analysis provides a comprehensive view of the entire technology area, helping to identify trends and saturation levels.

What tools are available for conducting a patent landscape analysis?

Tools include the USPTO's Patent Public Search, Global Dossier, Common Citation Document (CCD), and Patent Examination Data System (PEDS).

How can patent landscape analysis help in licensing and collaboration?

By identifying companies with complementary technologies, businesses can explore licensing and collaboration opportunities that drive innovation and reduce the risk of patent infringement.

Sources

  1. US Patent 9487809B2 - Decreasing lactate level and increasing polypeptide production by downregulating the expression of lactate dehydrogenase and pyruvate dehydrogenase kinase.
  2. USPTO Paper 20 - Inter partes review of claims 1–20 of U.S Patent No. 10,299,336 B2.
  3. AcclaimIP - Patent Landscape Analysis - Uncovering Strategic Insights.
  4. USPTO - Search for patents - USPTO.

More… ↓

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Details for Patent 10,011,856

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Genentech, Inc. AVASTIN bevacizumab Injection 125085 February 26, 2004 10,011,856 2036-09-16
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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