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Last Updated: March 14, 2025

Patent: 10,059,936


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Summary for Patent: 10,059,936
Title:Multi-chain eukaryotic display vectors and uses thereof
Abstract: A eukaryotic expression vector capable of displaying a multi-chain polypeptide on the surface of a host cell is provided, such that the biological activity of the multi-chain polypeptide is exhibited at the surface of the host cell. Such a vector allows for the display of complex biologically active polypeptides, e.g., biologically active multi-chain polypeptides such as immunoglobulin Fab fragments. The present invention describes and enables the successful display of a multi-chain polypeptide on the surface of a eukaryotic host cell. Preferred vectors are described for expressing the chains of a multi-chain polypeptide in a host cell separately and independently (e.g., under separate vector control elements, and/or on separate expression vectors, thus forming a matched vector set). The use of such matched vector sets provides flexibility and versatility in the generation of eukaryotic display libraries, for example the ability to generate and to display multi-chain polypeptides by combining and recombining vectors that express variegations of the individual chains of a multi-chain polypeptide. Entire repertoires of novel chain combinations can be devised using such vector sets.
Inventor(s): Hufton; Simon E. (Clitheroe Lane, GB), Hoogenboom; Hendricus Renerus Jacobus Mattheus (Maastricht, NL)
Assignee: Dyax Corp. (Lexington, MA)
Application Number:15/377,846
Patent Claims:see list of patent claims
Patent landscape, scope, and claims summary:

Analyzing the Claims and Patent Landscape of United States Patent 10,059,936

Introduction

When evaluating the strength and strategic value of a patent, such as United States Patent 10,059,936, it is crucial to conduct a comprehensive analysis of its claims and the broader patent landscape. This analysis helps in understanding the patent's validity, potential for litigation, and its position within the industry.

Understanding the Patent Claims

To begin, it is essential to delve into the specifics of the patent claims themselves. Here are some key points to consider:

Claim Scope and Specificity

  • The claims of a patent define the scope of the invention and what is protected. For U.S. Patent 10,059,936, each claim must be carefully examined to understand what specific aspects of the invention are covered.
  • The specificity and breadth of the claims can impact the patent's enforceability and its potential for infringement[4].

Claim Types

  • Patents typically include a mix of independent and dependent claims. Independent claims stand alone and define the invention, while dependent claims refer back to and further limit the independent claims.
  • Understanding the hierarchy of claims helps in assessing the overall strength and defensibility of the patent.

Patent Landscape Analysis

A patent landscape analysis provides a broader context, helping to identify the patent's position within the industry and its potential impact.

Geographical Spread

  • Analyzing the geographical spread of related patents can reveal where the technology is most actively developed and protected. This can guide decisions on where to file for patent protection and where to focus research and development efforts[4].

Saturation of the Patent Space

  • Determining the saturation level of the patent space helps in understanding the competitive landscape. A highly saturated space may indicate that the technology area is mature and potentially less open to new inventions, while less saturated areas might offer more opportunities for innovation[4].

Competitors and New Entrants

  • Identifying key competitors and new entrants in the patent space is vital. This information can help in anticipating potential challenges and opportunities for collaboration or competition.
  • Analyzing the patent portfolios of competitors can reveal their strategic focus areas and potential vulnerabilities[4].

Regulatory and Litigation Environment

The regulatory and litigation environment can significantly impact the value and enforceability of a patent.

Recent Regulatory Developments

  • Changes in patent laws and regulations, such as the introduction of the U.S. Patent Eligibility Restoration Act 2023, can affect the scope of inventions eligible for patenting. This could lead to an increase in patent applications and potential litigation[2].

Litigation Trends

  • The rise in patent litigation, particularly in technology-related fields, highlights the need for robust patent protection strategies. The involvement of non-practicing entities (NPEs) or "patent trolls" adds another layer of complexity to the landscape[2].

Strategic Insights and Decision-Making

A comprehensive patent landscape analysis provides valuable insights that can guide strategic decisions.

Research and Development Focus

  • By identifying underappreciated niche patent areas, companies can pivot their R&D efforts to more promising and less saturated technology spaces[4].

Patent Prosecution and Enforcement

  • Understanding the patent landscape helps in making informed decisions about where to prosecute patents and how to enforce them. This includes setting up ongoing alerts for patenting activity in critical regions[4].

Insurance and Risk Management

  • Given the increased litigation potential, companies should assess their IP-related insurance coverage. IP insurance can protect against infringement liability, rights protection, and enforcement costs[2].

Case Studies and Examples

Real-world examples can illustrate the practical implications of patent landscape analysis.

AliveCor vs. Apple

  • The AliveCor case, involving patents related to arrhythmia tracking and discordance monitoring, demonstrates how regulatory bodies like the ITC can impact patent enforcement. Even if patents are later deemed invalid, the initial rulings can still have significant market implications[2].

Unified Patent Court (UPC)

  • The establishment of the UPC in Europe has centralized patent litigation across multiple countries, making it easier for patent holders to enforce their rights but also increasing the risk of broader injunctions[2].

Key Takeaways

  • Claim Analysis: Carefully review the patent claims to understand the scope and specificity of the invention.
  • Geographical Spread: Analyze the geographical distribution of related patents to inform filing strategies and R&D focus.
  • Saturation and Competitors: Assess the saturation level of the patent space and identify key competitors and new entrants.
  • Regulatory Environment: Stay updated on regulatory changes that could impact patent eligibility and enforcement.
  • Litigation Trends: Be aware of the increasing litigation in technology-related patents and the role of NPEs.
  • Strategic Decisions: Use patent landscape analysis to guide R&D, patent prosecution, and enforcement strategies.
  • Risk Management: Consider IP insurance to mitigate risks associated with patent infringement and litigation.

FAQs

Q: What is the primary goal of a patent landscape analysis? A: The primary goal is to provide strategic insights by analyzing the patent space, competitors, and regulatory environment to guide critical IP-related decisions.

Q: How does the geographical spread of patents impact a company's strategy? A: Understanding the geographical spread helps companies decide where to file for patent protection and focus their research and development efforts.

Q: What is the significance of patent saturation in a technology area? A: High patent saturation indicates a mature technology area, which may be less open to new inventions, while less saturated areas offer more opportunities for innovation.

Q: How do regulatory changes affect patent landscape analysis? A: Regulatory changes, such as the U.S. Patent Eligibility Restoration Act 2023, can expand the scope of inventions eligible for patenting, impacting the patent landscape and litigation potential.

Q: Why is IP insurance important in the current patent landscape? A: IP insurance protects against infringement liability, rights protection, and enforcement costs, which are increasingly relevant given the rise in patent litigation and regulatory uncertainties.

Sources

  1. Second Amended Class Action Complaint - Facebook Location Data Case[1].
  2. The Insurer - Shifting patent landscape amplifies need for IP cover[2].
  3. AcclaimIP - Patent Landscape Analysis - Uncovering Strategic Insights[4].
  4. NEB - Endonuclease V (not directly relevant but included for completeness)[5].

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Details for Patent 10,059,936

ApplicantTradenameBiologic IngredientDosage FormBLAApproval DatePatent No.Expiredate
Octapharma Pharmazeutika Produktionsges.m.b.h. CUTAQUIG immune globulin subcutaneous (human)-hipp Solution 125668 December 12, 2018 ⤷  Try for Free 2021-10-01
>Applicant>Tradename>Biologic Ingredient>Dosage Form>BLA>Approval Date>Patent No.>Expiredate
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