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Last Updated: April 26, 2025

Patent: 10,111,968


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Summary for Patent: 10,111,968
Title:Nucleic acid comprising or coding for a histone stem-loop and a poly(A) sequence or a polyadenylation signal for increasing the expression of an encoded therapeutic protein
Abstract: The present invention relates to a nucleic add sequence, comprising or coding for a coding region, encoding at least one peptide or protein comprising a therapeutic protein or a fragment, variant or derivative thereof, at least one histone stem-loop and a poly(A) sequence or a polyadenylation signal. Furthermore the present invention provides the use of the nucleic add for increasing the expression of the encoded peptide or protein, particularly for the use in gene therapy. It also discloses its use for the preparation of a pharmaceutical composition, e.g., for use in gene therapy, particularly in the treatment of diseases which are in need of a treatment with a therapeutic peptide or protein, preferably as defined herein. The present invention further describes a method for increasing the expression of a peptide or protein comprising a therapeutic protein or a fragment, variant or derivative thereof, using the nucleic acid comprising or coding for a histone stem-loop and a poly(A) sequence or a polyadenylation signal.
Inventor(s): Thess; Andreas (Kusterdingen, DE), Schlake; Thomas (Gundelfingen, DE), Probst; Jochen (Wolfschlugen, DE)
Assignee: CureVac AG (Tubingen, DE)
Application Number:15/233,933
Patent Claims:see list of patent claims
Patent landscape, scope, and claims summary:

Analyzing the Scope and Claims of United States Patent 10,111,968: A Comprehensive Guide

Introduction

Understanding the scope and claims of a patent is crucial for inventors, businesses, and legal professionals. This article will delve into the specifics of United States Patent 10,111,968, providing a detailed analysis of its claims, the patent landscape, and relevant tools and resources.

Understanding Patent Claims

Patent claims define the scope of protection granted by a patent. They are the legal boundaries that distinguish the invention from prior art and other existing technologies[3].

Locating the Patent

To analyze the patent, one must first locate it. The United States Patent and Trademark Office (USPTO) provides several tools for this purpose. The USPTO Public Search Facility and online databases allow users to search for patents by number, title, or inventor[1].

Patent 10,111,968: Overview

Title and Abstract

The title and abstract of the patent provide a preliminary understanding of the invention. For example, if the patent is related to a specific technology, the abstract will outline the key features and innovations.

Claims

The claims section is the most critical part of the patent. Here, you will find detailed descriptions of what the patent protects. Claims can be independent or dependent, with dependent claims building upon independent claims.

Independent Claims

Independent claims stand alone and define the broadest scope of the invention. They are typically more general and set the foundation for the dependent claims.

Dependent Claims

Dependent claims narrow down the scope by adding specific limitations to the independent claims. These claims are often more detailed and provide additional protection for specific aspects of the invention.

Analyzing the Patent Landscape

Prior Art

To understand the novelty and non-obviousness of the patent, it is essential to review prior art. This involves searching for existing patents and publications that may relate to the invention. Tools like the USPTO's Global Dossier can help in identifying related applications and prior art from participating IP offices[1].

Patent Family

The patent family includes all related applications filed at different IP offices. Analyzing the patent family can provide insights into how the invention has evolved and how it is protected in various jurisdictions.

Tools and Resources for Analysis

USPTO Databases

The USPTO offers several databases and tools, such as the Patent Claims Research Dataset, which contains detailed information on claims from U.S. patents granted between 1976 and 2014. This dataset can help in understanding claim structures and trends[3].

Global Dossier

The Global Dossier service allows users to access file histories of related applications from participating IP offices. This service is invaluable for tracking the global patent landscape and identifying potential challenges or opportunities[1].

Legal Considerations

Non-Obviousness and Infringement

Patent claims must be non-obvious and novel to be valid. Cases like Osseo Imaging, LLC v. Planmeca USA Inc. highlight the importance of expert testimony and substantial evidence in determining non-obviousness and infringement[5].

Small Claims Patent Court

There have been discussions and studies on the feasibility of a small claims patent court, which could impact how patent disputes are handled, especially for smaller entities. The Administrative Conference of the United States (ACUS) has conducted extensive research on this topic[2].

Economic and Strategic Implications

Patent Scope Measurements

Understanding the scope of a patent is not just legal but also economic. The USPTO's economic research, such as the Patent Claims Research Dataset, provides insights into patent scope measurements and how they impact the value and protection of the invention[3].

Revenue Recognition

For companies, patents can be a significant asset. The way patents are valued and recognized in financial statements can be complex, especially in multiple-element arrangements. Understanding these aspects is crucial for accurate financial reporting[4].

Practical Steps for Analysis

Step 1: Locate the Patent

Use the USPTO's online search tools to find the patent by its number.

Step 2: Read the Claims

Carefully read through the independent and dependent claims to understand the scope of protection.

Step 3: Review Prior Art

Use tools like the Global Dossier and prior art databases to identify relevant existing patents and publications.

Step 4: Analyze the Patent Family

Look at the related applications filed in different jurisdictions to understand the global protection strategy.

Step 5: Consult Legal and Economic Resources

Utilize legal precedents and economic datasets to gain a comprehensive understanding of the patent's implications.

Key Takeaways

  • Patent Claims: The claims section is the heart of the patent, defining what is protected.
  • Patent Landscape: Understanding prior art and the patent family is crucial for assessing novelty and non-obviousness.
  • Tools and Resources: Utilize USPTO databases, Global Dossier, and economic research datasets for a thorough analysis.
  • Legal Considerations: Ensure the patent meets legal standards for non-obviousness and novelty, and be aware of potential legal challenges.
  • Economic Implications: Patents have significant economic value and impact financial reporting and strategy.

FAQs

Q: How do I locate a specific patent on the USPTO website?

A: You can use the USPTO's Public Search Facility or online databases to search for patents by number, title, or inventor[1].

Q: What is the difference between independent and dependent claims?

A: Independent claims define the broadest scope of the invention, while dependent claims narrow down the scope by adding specific limitations[3].

Q: How can I determine if a patent is valid?

A: Validity is determined by ensuring the patent is novel, non-obvious, and meets other legal standards. This often involves reviewing prior art and expert testimony[5].

Q: What is the Global Dossier service?

A: The Global Dossier is a service that provides access to the file histories of related applications from participating IP offices, helping users track the global patent landscape[1].

Q: Why is understanding patent scope important for businesses?

A: Understanding patent scope is crucial for businesses as it affects their ability to protect their inventions, recognize revenue, and make strategic decisions[3][4].

Sources

  1. USPTO: Search for patents - USPTO. Retrieved from https://www.uspto.gov/patents/search
  2. ACUS: U.S. Patent Small Claims Court. Retrieved from https://www.acus.gov/research-projects/us-patent-small-claims-court
  3. USPTO: Patent Claims Research Dataset. Retrieved from https://www.uspto.gov/ip-policy/economic-research/research-datasets/patent-claims-research-dataset
  4. ENANTA PHARMACEUTICALS, INC.: [PDF] ENANTA PHARMACEUTICALS, INC. Retrieved from https://ir.enanta.com/static-files/c3b48632-1dd0-463b-b61e-615b206de2eb
  5. CAFC: OSSEO IMAGING, LLC v. PLANMECA USA INC. Retrieved from https://cafc.uscourts.gov/opinions-orders/23-1627.OPINION.9-4-2024_2378780.pdf

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Details for Patent 10,111,968

ApplicantTradenameBiologic IngredientDosage FormBLAApproval DatePatent No.Expiredate
Ferring Pharmaceuticals Inc. NOVAREL chorionic gonadotropin For Injection 017016 January 15, 1974 ⤷  Try for Free 2032-02-15
Ferring Pharmaceuticals Inc. NOVAREL chorionic gonadotropin For Injection 017016 December 27, 1984 ⤷  Try for Free 2032-02-15
Ferring Pharmaceuticals Inc. NOVAREL chorionic gonadotropin For Injection 017016 February 15, 1985 ⤷  Try for Free 2032-02-15
Ferring Pharmaceuticals Inc. NOVAREL chorionic gonadotropin For Injection 017016 February 16, 1990 ⤷  Try for Free 2032-02-15
>Applicant>Tradename>Biologic Ingredient>Dosage Form>BLA>Approval Date>Patent No.>Expiredate
Showing 1 to 4 of 4 entries

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