Patent: 6,355,245

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Summary for Patent: 6,355,245

Title:	C5-specific antibodies for the treatment of inflammatory diseases
Abstract:	The use of anti-C5 antibodies, e.g., monoclonal antibodies, to treat glomerulonephritis (GN) is disclosed. The administration of such antibodies at low dosage levels has been found to significantly reduce glomerular inflammation/enlargement and other pathologic conditions associated with GN. Also disclosed are anti-C5 antibodies and anti-C5 antibody-encoding nucleic acid molecules. These antibodies are useful in the treatment of GN and other inflammatory conditions involving pathologic activation of the complement system.
Inventor(s):	Evans; Mark J. (Cheshire, CT), Matis; Louis A. (Southport, CT), Mueller; Eileen Elliott (East Haven, CT), Nye; Steven H. (Mequon, WI), Rollins; Scott (Monroe, CT), Rother; Russell P. (Cheshire, CT), Springhorn; Jeremy P. (Cheshire, CT), Squinto; Stephen P. (Bethany, CT), Thomas; Thomas C. (Madison, CT), Wilkins; James A. (Woodbridge, CT)
Assignee:	Alexion Pharmaceuticals, Inc. (Cheshire, CT)
Application Number:	08/487,283
Patent Claims:	see list of patent claims

Details for Patent 6,355,245

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Alexion Pharmaceuticals, Inc.	SOLIRIS	eculizumab	Injection	125166	March 16, 2007	⤷ Sign Up	2019-03-12
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 6,355,245

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Country	Patent Number	Estimated Expiration
World Intellectual Property Organization (WIPO)	9529697	⤷ Sign Up
United States of America	6074642	⤷ Sign Up
Portugal	758904	⤷ Sign Up
Netherlands	300433	⤷ Sign Up
>Country	>Patent Number	>Estimated Expiration

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