Patent: 6,858,409

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Summary for Patent: 6,858,409

Title:	Nucleic acids encoding interleukin-1 inhibitors and processes for preparing interleukin-1 inhibitors
Abstract:	Compounds are disclosed having the general formula R.sub.1 --X--R.sub.2, wherein R.sub.1 and R.sub.2 are biologically active groups, at least one of which is polypeptidic. X is a non-peptidic polymeric group. R.sub.1 and R.sub.2 may be the same or different. Preferred R.sub.1 and R.sub.2 groups are interleukin-1 receptor antagonist, 30 kDa TNF inhibitor, interleukin-2 receptors and CR1 and muteins thereof. Also included are site selectively modified interleukin-1 receptor antagonist and 30 kDa TNF inhibitor.
Inventor(s):	Thompson; Robert C. (Boulder, CO), Hannum; Charles H. (Sunnyvale, CA), Eisenberg; Stephen P. (Boulder, CO), Arend; William P. (Denver, CO), Joslin; Fenneke G. (Denver, CO), Sommer; Andreas (Danville, CA)
Assignee:	Amgen Inc. (Thousand Oaks, CA) The Regents of the University of Colorado (Boulder, CO)
Application Number:	08/482,283
Patent Claims:	see list of patent claims

Details for Patent 6,858,409

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Swedish Orphan Biovitrum Ab (publ)	KINERET	anakinra	Injection	103950	November 14, 2001	⤷ Sign Up	2022-02-22
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 6,858,409

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Austria	E215966	⤷ Sign Up
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Australia	1674292	⤷ Sign Up
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