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Last Updated: December 15, 2024

Patent: 9,522,953


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Summary for Patent: 9,522,953
Scope and claims summary:
Title:Low acidic species compositions and methods for producing and using the same
Abstract: The instant invention relates to low acidic species (AR) compositions comprising a protein, e.g., an antibody, or antigen-binding portion thereof, and methods, e.g., cell culture and/or protein purification methods, for producing such low AR compositions. Methods for using such compositions to treat a disorder, e.g., a disorder in which TNF.alpha. is detrimental, are also provided.
Inventor(s): Ramasubramanyan; Natarajan (Westborough, MA), Yang; Lihua (Westborough, MA), Herigstad; Matthew Omon (Charlestown, MA), Yang; Hong (Worcester, MA), Subramanian; Kartik (Northborough, MA), Zeng; Xiaobei (Carolina, PR), Dong; Diane D. (Shrewsbury, MA), Lim; Wen Chung (Worcester, MA), Gifford; Kathreen A. (Marlborough, MA), Kaymakcalan; Zehra (Westborough, MA), Chumsae; Christopher (North Andover, MA)
Assignee: ABBVIE, INC. (North Chicago, IL)
Application Number:15/009,286
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 9,522,953
Patent Claims:see list of patent claims

Details for Patent 9,522,953

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Abbvie Inc. HUMIRA adalimumab Injection 125057 December 31, 2002 9,522,953 2033-10-18
Abbvie Inc. HUMIRA adalimumab Injection 125057 February 21, 2008 9,522,953 2033-10-18
Abbvie Inc. HUMIRA adalimumab Injection 125057 April 24, 2013 9,522,953 2033-10-18
Abbvie Inc. HUMIRA adalimumab Injection 125057 September 23, 2014 9,522,953 2033-10-18
Abbvie Inc. HUMIRA adalimumab Injection 125057 November 23, 2015 9,522,953 2033-10-18
Abbvie Inc. HUMIRA adalimumab Injection 125057 March 09, 2016 9,522,953 2033-10-18
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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