Patent: 9,522,953
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Summary for Patent: 9,522,953
Title: | Low acidic species compositions and methods for producing and using the same |
Abstract: | The instant invention relates to low acidic species (AR) compositions comprising a protein, e.g., an antibody, or antigen-binding portion thereof, and methods, e.g., cell culture and/or protein purification methods, for producing such low AR compositions. Methods for using such compositions to treat a disorder, e.g., a disorder in which TNF.alpha. is detrimental, are also provided. |
Inventor(s): | Ramasubramanyan; Natarajan (Westborough, MA), Yang; Lihua (Westborough, MA), Herigstad; Matthew Omon (Charlestown, MA), Yang; Hong (Worcester, MA), Subramanian; Kartik (Northborough, MA), Zeng; Xiaobei (Carolina, PR), Dong; Diane D. (Shrewsbury, MA), Lim; Wen Chung (Worcester, MA), Gifford; Kathreen A. (Marlborough, MA), Kaymakcalan; Zehra (Westborough, MA), Chumsae; Christopher (North Andover, MA) |
Assignee: | ABBVIE, INC. (North Chicago, IL) |
Application Number: | 15/009,286 |
Patent Litigation and PTAB cases: | See patent lawsuits and PTAB cases for patent 9,522,953 |
Patent Claims: | see list of patent claims |
Details for Patent 9,522,953
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Abbvie Inc. | HUMIRA | adalimumab | Injection | 125057 | December 31, 2002 | 9,522,953 | 2033-10-18 |
Abbvie Inc. | HUMIRA | adalimumab | Injection | 125057 | February 21, 2008 | 9,522,953 | 2033-10-18 |
Abbvie Inc. | HUMIRA | adalimumab | Injection | 125057 | April 24, 2013 | 9,522,953 | 2033-10-18 |
Abbvie Inc. | HUMIRA | adalimumab | Injection | 125057 | September 23, 2014 | 9,522,953 | 2033-10-18 |
Abbvie Inc. | HUMIRA | adalimumab | Injection | 125057 | November 23, 2015 | 9,522,953 | 2033-10-18 |
Abbvie Inc. | HUMIRA | adalimumab | Injection | 125057 | March 09, 2016 | 9,522,953 | 2033-10-18 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |