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Last Updated: December 21, 2024

QUADRACEL Drug Profile


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Summary for Tradename: QUADRACEL
High Confidence Patents:0
Applicants:1
BLAs:1
Note on Biologic Patents

Matching patents to biologic drugs is far more complicated than for small-molecule drugs.

DrugPatentWatch employs three methods to identify biologic patents:

  1. Brand-side disclosures in response to biosimilar applications
  2. These patents were identified from disclosures by the brand-side company, in response to a potential biosimilar seeking to launch. They have a high certainty of blocking biosimilar entry. The expiration dates listed are not estimates — they're expiration dates as indicated by the brand-side company.

  3. General brand-side disclosures
  4. These patents were identified from searching drug labels and other general disclosures from the brand-side company. This list may exclude some of the patents which block biosimilar launch, and some of these patents listed may not actually block biosimilar launch. The expiration dates listed for these patents are estimates, based on the grant date of the patent.

  5. Patents from broad patent text search
  6. For completeness, these patents were identified by searching the patent literature for mentions of the branded or ingredient name of the drug. Some of these patents protect the original drug, whereas others may protect follow-on inventions or even inventions casually mentioning the drug. The expiration dates listed for these patents are estimates, based on the grant date of the patent.

1) High Certainty: US Patents for QUADRACEL Derived from Brand-Side Litigation

No patents found based on brand-side litigation

2) High Certainty: US Patents for QUADRACEL Derived from Company Disclosures

No patents found based on company disclosures

3) Low Certainty: US Patents for QUADRACEL Derived from Patent Text Search

No patents found based on company disclosures

QUADRACEL Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for the Biologic Drug: Quadracel

Introduction to Quadracel

Quadracel is a combined vaccine indicated for active immunization against diphtheria, tetanus, pertussis, and poliomyelitis. It is designed to protect against these serious diseases, particularly in children and adolescents. Understanding the market dynamics and financial trajectory of Quadracel involves examining several key factors, including market size, growth drivers, competitive landscape, and financial performance.

Market Size and Growth of DTP Vaccines

The global DTP vaccines market, which includes Quadracel, is significant and growing. As of 2022, the market size was approximately $6.02 billion and is expected to grow to $6.39 billion in 2023, representing a compound annual growth rate (CAGR) of 6.1%[4].

Long-Term Projections

By 2027, the DTP vaccines market is projected to reach $7.79 billion, growing at a CAGR of 5.1%. This growth is driven by increasing demand for vaccines, particularly in regions with high birth rates and where vaccination programs are being expanded or intensified[4].

Drivers of Market Growth

Several factors contribute to the growth of the DTP vaccines market, including:

Increasing Prevalence of Chronic and Infectious Diseases

The rising prevalence of infectious diseases, coupled with the need for preventive measures, drives the demand for vaccines like Quadracel. This is particularly true in regions with limited healthcare infrastructure where vaccines are a critical component of public health strategies[4].

Technological Advancements

Continuous technological advancements in vaccine development, including the creation of combination vaccines like Quadracel, enhance the efficacy and convenience of vaccination. These advancements also contribute to the market's growth by offering more targeted and effective therapies[3].

Regulatory Approvals and Reimbursement Policies

The approval of vaccines by regulatory agencies and favorable reimbursement policies in many countries support the market's expansion. These factors make vaccines more accessible and affordable, thereby increasing their adoption rates[3].

Competitive Landscape

The DTP vaccines market is competitive, with several key players offering various vaccines. Quadracel competes with other vaccines such as Daptacel, Infanrix, Kinrix, Pediarix, Pentacel, and Vaxelis.

Comparative Efficacy and Safety

Quadracel has demonstrated strong efficacy and safety profiles in clinical trials. For example, it has shown high booster response rates and geometric mean concentrations (GMC) for antibodies against pertussis and poliovirus components, comparable to or sometimes superior to other vaccines like Daptacel + IPOL[1].

Financial Performance

While specific financial data for Quadracel alone is not readily available, the overall financial performance of the companies involved in its production and distribution can provide insights.

Revenue and Market Share

The revenue generated from DTP vaccines, including Quadracel, contributes significantly to the overall revenue of pharmaceutical companies. For instance, the growth in the DTP vaccines market directly impacts the revenue of companies like Sanofi, which produces several DTP vaccines[4].

Operational Costs and Profit Margins

The production and distribution of vaccines involve significant operational costs, including research and development, manufacturing, and distribution. Companies in this sector often report gross margins that reflect these costs. For example, Quanterix, although not directly involved in vaccine production, reports gross margins that can provide a broader context on the industry's financial health[2].

Challenges and Opportunities

Supply Chain Disruptions

Global events such as the Russia-Ukraine war have caused supply chain disruptions, affecting the production and distribution of vaccines. These disruptions can impact the financial trajectory of vaccine manufacturers by increasing costs and reducing availability[4].

Expanding Healthcare Infrastructure

The expansion of healthcare infrastructure in developing countries presents a significant opportunity for the growth of the DTP vaccines market. As more countries invest in healthcare, the demand for vaccines like Quadracel is likely to increase[3].

Regulatory Environment

Approvals and Compliance

Regulatory approvals are crucial for the market success of any vaccine. Quadracel, like other vaccines, must comply with stringent regulatory requirements to ensure safety and efficacy. The approval process can be lengthy and costly but is essential for market entry[1].

Consumer Awareness and Acceptance

Increasing Awareness

Consumer awareness about the importance of vaccination is a key driver of the market. Educational campaigns and public health initiatives aimed at increasing vaccination rates contribute to the growth of the DTP vaccines market[3].

Key Takeaways

  • Market Growth: The DTP vaccines market, including Quadracel, is expected to grow significantly, driven by increasing demand and technological advancements.
  • Competitive Landscape: Quadracel competes in a competitive market with other DTP vaccines, but its efficacy and safety profile make it a strong contender.
  • Financial Performance: The financial performance of companies involved in vaccine production is influenced by market size, operational costs, and regulatory environments.
  • Challenges and Opportunities: Supply chain disruptions pose challenges, while expanding healthcare infrastructure presents opportunities for growth.

FAQs

What is Quadracel used for?

Quadracel is used for active immunization against diphtheria, tetanus, pertussis, and poliomyelitis.

How does Quadracel compare to other DTP vaccines in terms of efficacy?

Quadracel has shown high booster response rates and geometric mean concentrations (GMC) for antibodies against pertussis and poliovirus components, comparable to or sometimes superior to other vaccines like Daptacel + IPOL[1].

What are the key drivers of the DTP vaccines market?

The key drivers include increasing prevalence of infectious diseases, technological advancements, regulatory approvals, and favorable reimbursement policies[3][4].

How does the global economic environment impact the DTP vaccines market?

Global events like the Russia-Ukraine war can cause supply chain disruptions, affecting the production and distribution of vaccines and impacting their financial trajectory[4].

What is the projected market size of the DTP vaccines by 2027?

The DTP vaccines market is projected to reach $7.79 billion by 2027, growing at a CAGR of 5.1%[4].

Sources

  1. Quadracel® Diphtheria, Tetanus Toxoids and Pertussis Vaccine Adsorbed Combined with Inactivated Poliomyelitis Vaccine (IPV) for Intramuscular Injection. Quadracel.
  2. Quanterix Releases Financial Results for the Second Quarter of 2024. Quanterix.
  3. Biologics Market Size to Reach USD 699.5 Billion by 2032, Impelled by Emergence of Advanced Drug Delivery Systems. Biospace.
  4. DTP Vaccines Global Market Report 2023. PR Newswire.

More… ↓

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