Hypothesis A single subanesthetic dose of propofol will result in improved pain and quality
of life for the next 30 days in persons with chronic daily headache (CDH)
Specific objectives To measure the effect of a single infusion of propofol at 40 mcg / kg /
minute over 60 mins on headache-related quality of life (measured by the Headache Disability
Index) and on headache severity (measured by the Headache Index) in subjects with chronic
daily headache over 30 days45-47
TREXIMET® Versus Butalbital-containing Combination Medications for the Acute Treatment of Migraine in Adults
Completed
GlaxoSmithKline
Phase 3
2008-02-01
Study TRX109011/TRX109013, A Randomized, Double-blind, Double-dummy, Placebo-controlled,
Crossover Study to Evaluate the Efficacy of TREXIMET® (Sumatriptan + Naproxen Sodium) versus
Butalbital-containing Combination Medications (BCM) for the Acute Treatment of Migraine when
administered during the Moderate-Severe Pain Phase of the Migraine (Studies 1 and 2 of 2)
Therapeutic Equivalence Between Branded and Generic WARFArin Tablets in Brazil
Completed
Fundação de Amparo à Pesquisa do Estado de São Paulo
Phase 4
2014-08-01
The purpose of this study is to assess whether the switch from branded to generic warfarin or
between different generic warfarin tablets may cause fluctuation in the results of
coagulation tests (International Normalized Rate, acronym INR) in patients, thus predisposing
them to unnecessary risks.
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