Efficacy of Caffeine, With and Without Biperiden, as a Maintenance Treatment for Cocaine Dependence
Unknown status
Hospital Universitari Vall d'Hebron Research Institute
Phase 4
2009-01-01
The aim of this study is to assess the efficacy of caffeine compared to placebo as a
maintenance treatment for cocaine dependence. Caffeine potentiation with biperiden will be
also studied.
Ninety patients with snorted/sniffed cocaine dependence will be randomized to receive
caffeine (300 - 1200 mg t.i.d.) plus biperidene (8 mg b.i.d.) caffeine (300 - 1200 mg t.i.d.)
with placebo or placebo during 10 days in an in-hospital setting.
Use of Biperiden for the Prevention of Post-traumatic Epilepsy
Recruiting
Cristália Produtos Químicos Farmacêuticos Ltda.
Phase 3
2018-01-31
There is no AED or medication that has been demonstrated to affect the development of
post-traumatic epilepsy. Biperiden is a cholinergic antagonist, acting in the muscarinic
receptor, that is widely used as an anti Parkinson drug. The investigators data with animal
models of epilepsy indicate that anti-muscarinic agents might affect the natural course of
the disease in the case of post-traumatic epilepsy.
Use of Biperiden for the Prevention of Post-traumatic Epilepsy
Recruiting
University of Sao Paulo
Phase 3
2018-01-31
There is no AED or medication that has been demonstrated to affect the development of
post-traumatic epilepsy. Biperiden is a cholinergic antagonist, acting in the muscarinic
receptor, that is widely used as an anti Parkinson drug. The investigators data with animal
models of epilepsy indicate that anti-muscarinic agents might affect the natural course of
the disease in the case of post-traumatic epilepsy.
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors.
Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data.
The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free.
thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user.
Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.
Alerts Available With Subscription
Alerts are available for users with active subscriptions.
