CLINICAL TRIALS PROFILE FOR ALDARA
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All Clinical Trials for ALDARA
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT00079300 ↗ | Imiquimod Cream in Treating Patients With Basal Cell Skin Cancer | Completed | National Naval Medical Center | Phase 1 | 2004-01-01 | RATIONALE: Biological therapies, such as imiquimod cream, work in different ways to stimulate the immune system and stop tumor cells from growing. PURPOSE: This randomized phase I trial is studying how well imiquimod cream works in treating patients with basal cell skin cancer. |
| NCT00142454 ↗ | NY-ESO-1 Protein Vaccine With Imiquimod in Melanoma (Adjuvant Setting) | Completed | American Society of Clinical Oncology | Phase 1 | 2005-08-24 | This was a Phase 1, single-arm, open-label, pilot study of NY-ESO-1 protein vaccination with imiquimod as an adjuvant in patients with resected Stage IIB, IIC, and III malignant melanoma. The primary study objective was to determine the safety of NY-ESO-1 protein/imiquimod treatment, and the secondary objective was to evaluate the immunogenicity of treatment. |
| NCT00142454 ↗ | NY-ESO-1 Protein Vaccine With Imiquimod in Melanoma (Adjuvant Setting) | Completed | Cancer Research Institute (CRI) | Phase 1 | 2005-08-24 | This was a Phase 1, single-arm, open-label, pilot study of NY-ESO-1 protein vaccination with imiquimod as an adjuvant in patients with resected Stage IIB, IIC, and III malignant melanoma. The primary study objective was to determine the safety of NY-ESO-1 protein/imiquimod treatment, and the secondary objective was to evaluate the immunogenicity of treatment. |
| NCT00142454 ↗ | NY-ESO-1 Protein Vaccine With Imiquimod in Melanoma (Adjuvant Setting) | Completed | Ludwig Institute for Cancer Research | Phase 1 | 2005-08-24 | This was a Phase 1, single-arm, open-label, pilot study of NY-ESO-1 protein vaccination with imiquimod as an adjuvant in patients with resected Stage IIB, IIC, and III malignant melanoma. The primary study objective was to determine the safety of NY-ESO-1 protein/imiquimod treatment, and the secondary objective was to evaluate the immunogenicity of treatment. |
| NCT00176943 ↗ | Characteristics of T Cells From Alopecia Areata Scalp Skin Before and After Treatment With Aldara 5% | Completed | National Alopecia Areata Foundation | Phase 4 | 2000-10-01 | It is thought that alopecia areata occurs as the result of an inappropriate response of the body's own immune system to certain substances in or around the hair follicle. We will be examining the efficacy of Aldara Cream 5% in treating extensive alopecia areata and observe its affect on the hair follicle. |
| NCT00176943 ↗ | Characteristics of T Cells From Alopecia Areata Scalp Skin Before and After Treatment With Aldara 5% | Completed | Hordinsky, Maria K., MD | Phase 4 | 2000-10-01 | It is thought that alopecia areata occurs as the result of an inappropriate response of the body's own immune system to certain substances in or around the hair follicle. We will be examining the efficacy of Aldara Cream 5% in treating extensive alopecia areata and observe its affect on the hair follicle. |
| NCT00177021 ↗ | Aldara for the Treatment of Extensive Alopecia Areata | Completed | 3M | Phase 4 | 2000-10-01 | We propose to examine the efficacy and tolerability of Aldara Cream 5% for the treatment of extensive alopecia areata. Aldara is a immune-response modifier. The drug induces the production of cytokines which are small, hormone-like proteins involved in cellular communication during immune responses. We hypothesize that this drug will effect the inflammatory cells present around hair follicles in patients with alopecia areata. |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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