Proposed twin study will test to what degree inter-individual differences in pain sensitivity
and amount of pain relief in response to opioid therapy are inherited or alternatively, are
due to environmental factors. This knowledge is important to guide future studies trying to
explain such inter-individual differences. For example, finding that differences are largely
due to environmental factors would discourage genomic studies and emphasize epidemiological
studies.
Proposed twin study will test to what degree inter-individual differences in pain sensitivity
and amount of pain relief in response to opioid therapy are inherited or alternatively, are
due to environmental factors. This knowledge is important to guide future studies trying to
explain such inter-individual differences. For example, finding that differences are largely
due to environmental factors would discourage genomic studies and emphasize epidemiological
studies.
Alfentanil Versus Remifentanil in Patient-controlled Sedation During Endoscopic Retrograde Cholangiopancreatography (ERCP)
Completed
Helsinki University Central Hospital
Phase 4
2009-06-01
Self-administration of propofol and opioid mixture by the patient him- or herself
(patient-controlled sedation, PCS) could be successful alternative to the
anesthesiologists-managed deep sedation during endoscopic retrograde cholangiopancreatography
(ERCP). However, it is not known which opioid would be the most suitable for PCS. The aim of
this double-blind study was to compare remifentanil and alfentanil in PCS during ERCP.
Comparison of Propofol/Alfentanil With Propofol/Ketamine
Unknown status
Rabin Medical Center
N/A
2014-02-01
A prospective, randomized, patient-blinded comparison of the safety and efficacy of conscious
sedation by propofol/alfentanil with propofol/ketamine in patients undergoing flexible
fiberoptic bronchoscopy.
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