CLINICAL TRIALS PROFILE FOR AMINOPHYLLINE

All Clinical Trials for AMINOPHYLLINE

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00130598 ↗	PROVOCATION Trial - PROphylactic intraVenOus Hydration for Contrast Agent Toxicity PreventION	Completed	Swiss National Science Foundation	Phase 2/Phase 3	2005-06-01	Contrast nephropathy (CN) remains a common complication of radiographic procedures and an important cause of hospital-acquired acute renal failure. Only hydration with saline is uniformly accepted and used in clinical practice as a cornerstone for the prevention of CN. But the optimal preventive strategy for CN is not known. Sodium bicarbonate might be even more effective than hydration with sodium chloride for prophylaxis of CN. Therefore the aim of the study is to evaluate the efficacy of two regimens of sodium bicarbonate compared with a prolonged infusion of sodium chloride in the prevention of CN. Primary endpoint: Decrease in glomerular filtration rate (GFR) within 48 hours.
NCT00130598 ↗	PROVOCATION Trial - PROphylactic intraVenOus Hydration for Contrast Agent Toxicity PreventION	Completed	University Hospital, Basel, Switzerland	Phase 2/Phase 3	2005-06-01	Contrast nephropathy (CN) remains a common complication of radiographic procedures and an important cause of hospital-acquired acute renal failure. Only hydration with saline is uniformly accepted and used in clinical practice as a cornerstone for the prevention of CN. But the optimal preventive strategy for CN is not known. Sodium bicarbonate might be even more effective than hydration with sodium chloride for prophylaxis of CN. Therefore the aim of the study is to evaluate the efficacy of two regimens of sodium bicarbonate compared with a prolonged infusion of sodium chloride in the prevention of CN. Primary endpoint: Decrease in glomerular filtration rate (GFR) within 48 hours.
NCT00312273 ↗	Aminophylline in Bradyasystolic Cardiac Arrest	Completed	Heart and Stroke Foundation of Canada	Phase 2	2001-01-01	The purpose of this study is to evaluate the effect of aminophylline in patients with out-of-hospital bradyasystolic cardiac arrest.
NCT00312273 ↗	Aminophylline in Bradyasystolic Cardiac Arrest	Completed	Vancouver Coastal Health Research Institute	Phase 2	2001-01-01	The purpose of this study is to evaluate the effect of aminophylline in patients with out-of-hospital bradyasystolic cardiac arrest.
NCT00312273 ↗	Aminophylline in Bradyasystolic Cardiac Arrest	Completed	Vancouver General Hospital	Phase 2	2001-01-01	The purpose of this study is to evaluate the effect of aminophylline in patients with out-of-hospital bradyasystolic cardiac arrest.

Clinical Trial Conditions for AMINOPHYLLINE

Condition Name

Condition Name for AMINOPHYLLINE
Intervention	Trials
Acute Kidney Injury	5
Aminophylline	3
Chronic Obstructive Pulmonary Disease	2
Post-dural Puncture Headache	2

Condition MeSH

Condition MeSH for AMINOPHYLLINE
Intervention	Trials
Acute Kidney Injury	6
Wounds and Injuries	4
Post-Dural Puncture Headache	3
Headache	3

Clinical Trial Locations for AMINOPHYLLINE

Trials by Country

Trials by Country for AMINOPHYLLINE
Location	Trials
United States	13
Egypt	7
China	7
Italy	2
United Kingdom	2

Trials by US State

Trials by US State for AMINOPHYLLINE
Location	Trials
Illinois	3
Colorado	2
North Carolina	2
California	2
Oregon	1

Clinical Trial Progress for AMINOPHYLLINE

Clinical Trial Phase

Clinical Trial Phase for AMINOPHYLLINE
Clinical Trial Phase	Trials
Phase 4	12
Phase 3	3
Phase 2/Phase 3	2

Clinical Trial Status

Clinical Trial Status for AMINOPHYLLINE
Clinical Trial Phase	Trials
Completed	19
Not yet recruiting	9
Unknown status	4

Clinical Trial Sponsors for AMINOPHYLLINE

Sponsor Name

Sponsor Name for AMINOPHYLLINE
Sponsor	Trials
Tanta University	3
Rush University Medical Center	3
Defense Advanced Research Projects Agency	2

Sponsor Type

Sponsor Type for AMINOPHYLLINE
Sponsor	Trials
Other	47
U.S. Fed	3
Industry	1