CLINICAL TRIALS PROFILE FOR AMINOSALICYLIC ACID
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All Clinical Trials for AMINOSALICYLIC ACID
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT00000796 ↗ | A Prospective Study of Multidrug Resistance and a Pilot Study of the Safety of and Clinical and Microbiologic Response to Levofloxacin in Combination With Other Antimycobacterial Drugs for Treatment of Multidrug-Resistant Pulmonary Tuberculosis (MDR | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | N/A | 1969-12-31 | To determine the demographic, behavioral, clinical, and geographic risk factors associated with the occurrence of multidrug-resistant pulmonary tuberculosis (MDRTB). To evaluate the clinical and microbiological responses and overall survival of MDRTB patients who are treated with levofloxacin-containing multiple-drug regimens chosen from a hierarchical list. Per 9/28/94 amendment, to assess whether persistent or recurrent positive sputum cultures of patients who show failure or relapse are due to the same strain or reinfection with a new strain. Among TB patients, there has been an increase in progressive disease due to the emergence of antimycobacterial drug-resistant strains of Mycobacterium tuberculosis. Failure to identify patients at high risk for MDRTB increases the hazard for both treatment failure and development of resistance to additional therapeutic agents. Efforts to improve survival in patients with MDRTB will depend on improved methods of assessing the risk of acquisition of MDRTB and identifying drug susceptibility patterns in a timely fashion. |
| NCT00004288 ↗ | Phase II Pilot Study of Olsalazine for Ankylosing Spondylitis | Completed | University of Rochester | Phase 2 | 1996-05-01 | OBJECTIVES: I. Assess the safety and efficacy of olsalazine, a dimer of 5-aminosalicylic acid, in men with ankylosing spondylitis unresponsive to nonsteroidal anti-inflammatory drugs and physiotherapy. |
| NCT00004288 ↗ | Phase II Pilot Study of Olsalazine for Ankylosing Spondylitis | Completed | National Center for Research Resources (NCRR) | Phase 2 | 1996-05-01 | OBJECTIVES: I. Assess the safety and efficacy of olsalazine, a dimer of 5-aminosalicylic acid, in men with ankylosing spondylitis unresponsive to nonsteroidal anti-inflammatory drugs and physiotherapy. |
| NCT00004423 ↗ | Controlled Trial of 4-Aminosalicylic Acid in Patients With Small Bowel Crohn's Disease | Completed | University of Vermont | N/A | 1995-12-01 | OBJECTIVES: I. Assess the efficacy and safety of 4-aminosalicylic acid in patients with active Crohn's disease of the small bowel. |
| NCT00004810 ↗ | Phase II Placebo-Controlled Study of 4-Aminosalicylic Acid for Ulcerative Colitis | Completed | University of Vermont | Phase 2 | 1996-06-01 | OBJECTIVES: I. Assess the safety and efficacy of 4-aminosalicylic acid in patients with mildly to moderately severe ulcerative colitis. |
| NCT00004810 ↗ | Phase II Placebo-Controlled Study of 4-Aminosalicylic Acid for Ulcerative Colitis | Completed | National Center for Research Resources (NCRR) | Phase 2 | 1996-06-01 | OBJECTIVES: I. Assess the safety and efficacy of 4-aminosalicylic acid in patients with mildly to moderately severe ulcerative colitis. |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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