CLINICAL TRIALS PROFILE FOR ANAFRANIL

All Clinical Trials for ANAFRANIL

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00018200 ↗	Effect of Antidepressants on Back Pain	Completed	US Department of Veterans Affairs	Phase 2	1999-04-01	The purpose of this study is to determine whether different types of antidepressant medicines relieve back pain that has lasted at least six months on a daily basis. Study participants will be assigned to treatment with either a antidepressant acting on the serotonin system in the brain (fluoxetine), one acting on the noradrenaline system (desipramine, or to a control medication not expected to relieve pain (benztropine). Each participant will be seen at least nine times during their 12 weeks on medication. This is a phase 2/3, outpatient study.
NCT00018200 ↗	Effect of Antidepressants on Back Pain	Completed	VA Office of Research and Development	Phase 2	1999-04-01	The purpose of this study is to determine whether different types of antidepressant medicines relieve back pain that has lasted at least six months on a daily basis. Study participants will be assigned to treatment with either a antidepressant acting on the serotonin system in the brain (fluoxetine), one acting on the noradrenaline system (desipramine, or to a control medication not expected to relieve pain (benztropine). Each participant will be seen at least nine times during their 12 weeks on medication. This is a phase 2/3, outpatient study.
NCT00466609 ↗	Using Drug Augmentation to Treat Obsessive Compulsive Disorder Patients Who Did Not Respond to Previous Treatment	Completed	Conselho Nacional de Desenvolvimento Científico e Tecnológico	Phase 4	2007-05-01	This will be a controlled, randomized, double-blind and double-dummy study on the treatment augmentation strategy for obsessive compulsive disorder patients non-respondent to first line pharmacological treatment. The investigators will compare: fluoxetine maintenance at maximum dosage for additional 12 weeks; the association of fluoxetine with quetiapine; and the association of fluoxetine with clomipramine.
NCT00466609 ↗	Using Drug Augmentation to Treat Obsessive Compulsive Disorder Patients Who Did Not Respond to Previous Treatment	Completed	Fundação de Amparo à Pesquisa do Estado de São Paulo	Phase 4	2007-05-01	This will be a controlled, randomized, double-blind and double-dummy study on the treatment augmentation strategy for obsessive compulsive disorder patients non-respondent to first line pharmacological treatment. The investigators will compare: fluoxetine maintenance at maximum dosage for additional 12 weeks; the association of fluoxetine with quetiapine; and the association of fluoxetine with clomipramine.
NCT00466609 ↗	Using Drug Augmentation to Treat Obsessive Compulsive Disorder Patients Who Did Not Respond to Previous Treatment	Completed	Novartis	Phase 4	2007-05-01	This will be a controlled, randomized, double-blind and double-dummy study on the treatment augmentation strategy for obsessive compulsive disorder patients non-respondent to first line pharmacological treatment. The investigators will compare: fluoxetine maintenance at maximum dosage for additional 12 weeks; the association of fluoxetine with quetiapine; and the association of fluoxetine with clomipramine.
NCT00466609 ↗	Using Drug Augmentation to Treat Obsessive Compulsive Disorder Patients Who Did Not Respond to Previous Treatment	Completed	University of Sao Paulo	Phase 4	2007-05-01	This will be a controlled, randomized, double-blind and double-dummy study on the treatment augmentation strategy for obsessive compulsive disorder patients non-respondent to first line pharmacological treatment. The investigators will compare: fluoxetine maintenance at maximum dosage for additional 12 weeks; the association of fluoxetine with quetiapine; and the association of fluoxetine with clomipramine.

Clinical Trial Conditions for ANAFRANIL

Condition Name

Condition Name for ANAFRANIL
Intervention	Trials
Obsessive Compulsive Disorder	3
Back Pain	2
Depression	2
Major Depression	1

Condition MeSH

Condition MeSH for ANAFRANIL
Intervention	Trials
Depression	3
Obsessive-Compulsive Disorder	3
Disease	3
Compulsive Personality Disorder	3

Clinical Trial Locations for ANAFRANIL

Trials by Country

Trials by Country for ANAFRANIL
Location	Trials
United States	2
Brazil	2
Canada	1
Israel	1

Trials by US State

Trials by US State for ANAFRANIL
Location	Trials
California	2

Clinical Trial Progress for ANAFRANIL

Clinical Trial Phase

Clinical Trial Phase for ANAFRANIL
Clinical Trial Phase	Trials
Phase 4	2
Phase 2	2
Phase 1	2

Clinical Trial Status

Clinical Trial Status for ANAFRANIL
Clinical Trial Phase	Trials
Completed	8

Clinical Trial Sponsors for ANAFRANIL

Sponsor Name

Sponsor Name for ANAFRANIL
Sponsor	Trials
VA Office of Research and Development	2
Conselho Nacional de Desenvolvimento Científico e Tecnológico	2
University of Sao Paulo	2

Sponsor Type

Sponsor Type for ANAFRANIL
Sponsor	Trials
Other	13
U.S. Fed	3
Industry	3