CLINICAL TRIALS PROFILE FOR AQUASOL A

All Clinical Trials for AQUASOL A

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00417404 ↗	Vitamin A and Very Low Birthweight Babies (VitAL)	Completed	Chief Scientist Office of the Scottish Government	Phase 4	2007-01-01	Vitamin A is important for the development of healthy eyes and lungs. Very low birth weight premature babies have low body stores of vitamin A and are prone to diseases of the eye and lungs. Previous work has shown that intramuscular (IM) vitamin A reduces the number of babies who require prolonged oxygen therapy, and may also reduce the number of babies affected by retinopathy of prematurity (ROP)). There is also some evidence that the conjunctiva shows signs of deficiency of vitamin A in premature infants, particularly those who develop ROP. Our own work here in Glasgow suggests that, compared to babies born at full term, premature babies' eyes are less sensitive to light and we believe that this may reflect shortage of vitamin A in the eye. This study will examine the effects upon the eye of giving extra intramuscular vitamin A to very low birth weight, premature infants. We will also measure blood levels of vitamin A and calculate liver stores of this nutrient.
NCT00417404 ↗	Vitamin A and Very Low Birthweight Babies (VitAL)	Completed	Glasgow Royal Infirmary	Phase 4	2007-01-01	Vitamin A is important for the development of healthy eyes and lungs. Very low birth weight premature babies have low body stores of vitamin A and are prone to diseases of the eye and lungs. Previous work has shown that intramuscular (IM) vitamin A reduces the number of babies who require prolonged oxygen therapy, and may also reduce the number of babies affected by retinopathy of prematurity (ROP)). There is also some evidence that the conjunctiva shows signs of deficiency of vitamin A in premature infants, particularly those who develop ROP. Our own work here in Glasgow suggests that, compared to babies born at full term, premature babies' eyes are less sensitive to light and we believe that this may reflect shortage of vitamin A in the eye. This study will examine the effects upon the eye of giving extra intramuscular vitamin A to very low birth weight, premature infants. We will also measure blood levels of vitamin A and calculate liver stores of this nutrient.
NCT01193270 ↗	Vitamin E for Extremely Preterm Infants	Completed	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	Phase 1	2010-10-01	The purpose of this pilot trial is to test the safety and efficacy of administering one dose of vitamin E, via a tube into the stomach, to extremely preterm infants (less than 27 weeks gestation and less than 1000 grams birth weight). This pilot will examine whether a single dose of vitamin E will be absorbed into the infants' bloodstreams with resulting serum α-tocopherol level in the target range of 1-3 mg/dl.
NCT01193270 ↗	Vitamin E for Extremely Preterm Infants	Completed	National Center for Research Resources (NCRR)	Phase 1	2010-10-01	The purpose of this pilot trial is to test the safety and efficacy of administering one dose of vitamin E, via a tube into the stomach, to extremely preterm infants (less than 27 weeks gestation and less than 1000 grams birth weight). This pilot will examine whether a single dose of vitamin E will be absorbed into the infants' bloodstreams with resulting serum α-tocopherol level in the target range of 1-3 mg/dl.
NCT01193270 ↗	Vitamin E for Extremely Preterm Infants	Completed	NICHD Neonatal Research Network	Phase 1	2010-10-01	The purpose of this pilot trial is to test the safety and efficacy of administering one dose of vitamin E, via a tube into the stomach, to extremely preterm infants (less than 27 weeks gestation and less than 1000 grams birth weight). This pilot will examine whether a single dose of vitamin E will be absorbed into the infants' bloodstreams with resulting serum α-tocopherol level in the target range of 1-3 mg/dl.
NCT03510962 ↗	Comparison of 5 Buffering Agents on Changes in Salivary pH in Individuals Previously Exposed to a Test Fruit Juice	Completed	Dr Meru S	N/A	2018-04-25	The diurnal variation in the flow of saliva and hence the composition of saliva is an established fact. Consumption of most types of acidic and sweetened foods and beverages are known to reduce the pH of saliva and some of them even reduce it to critical pH levels and result in structural damage to the hard tissues of the tooth. The purpose of this study is to ascertain the effect of the selected commercially available test fruit-juice drink on the salivary pH and assess the buffering capacity of the saliva with or without various intervention measures following the exposure to the test fruit-juice drink at different time intervals.

Clinical Trial Conditions for AQUASOL A

Condition Name

Condition Name for AQUASOL A
Intervention	Trials
Saliva Altered	2
Tooth Structure; Disorder	2
Oral Hygiene	2
pH	2

Condition MeSH

Condition MeSH for AQUASOL A
Intervention	Trials
Birth Weight	2
Hemorrhage	1
Retinopathy of Prematurity	1
Premature Birth	1

Clinical Trial Locations for AQUASOL A

Trials by Country

Trials by Country for AQUASOL A
Location	Trials
United States	14
India	2
United Kingdom	1

Trials by US State

Trials by US State for AQUASOL A
Location	Trials
Utah	1
Texas	1
Rhode Island	1
Ohio	1
North Carolina	1

Clinical Trial Progress for AQUASOL A

Clinical Trial Phase

Clinical Trial Phase for AQUASOL A
Clinical Trial Phase	Trials
Phase 4	1
Phase 1	1
N/A	2

Clinical Trial Status

Clinical Trial Status for AQUASOL A
Clinical Trial Phase	Trials
Completed	4

Clinical Trial Sponsors for AQUASOL A

Sponsor Name

Sponsor Name for AQUASOL A
Sponsor	Trials
Dr Meru S	2
Chief Scientist Office of the Scottish Government	1
Glasgow Royal Infirmary	1

Sponsor Type

Sponsor Type for AQUASOL A
Sponsor	Trials
Other	5
NIH	2