Pharmacokinetics/Pharmacodynamics of Argatroban Injection in End-Stage Renal Disease Patients Undergoing Hemodialysis
Completed
Texas Biotechnology Corporation
Phase 4
2002-05-01
The primary goals of this investigation are to provide guidance on how to dose Argatroban in
patients undergoing hemodialysis and to assess the safety and tolerability of Argatroban in
hemodialysis patients. The secondary goal of the study will be to assess the adequacy of
anticoagulation during hemodialysis.
Evaluation of Argatroban Injection in Pediatric Patients Requiring Anticoagulant Alternatives to Heparin
Completed
GlaxoSmithKline
Phase 4
2003-09-01
The purpose of this study is to evaluate the safe and effective dose of Argatroban for
prophylaxis and/or treatment of thrombosis in pediatric patients with current or previous
diagnosis of heparin-induced thrombocytopenia (HIT) and thrombosis syndrome (HITTS), or who
in the opinion of the investigator require alternative anticoagulation due to an underlying
condition.
Evaluation of Argatroban Injection in Pediatric Patients Requiring Anticoagulant Alternatives to Heparin
Completed
Encysive Pharmaceuticals
Phase 4
2003-09-01
The purpose of this study is to evaluate the safe and effective dose of Argatroban for
prophylaxis and/or treatment of thrombosis in pediatric patients with current or previous
diagnosis of heparin-induced thrombocytopenia (HIT) and thrombosis syndrome (HITTS), or who
in the opinion of the investigator require alternative anticoagulation due to an underlying
condition.
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