You're using a free limited version of DrugPatentWatch: Upgrade for Complete Access

Last Updated: November 4, 2024

CLINICAL TRIALS PROFILE FOR ARSENIC TRIOXIDE


✉ Email this page to a colleague

« Back to Dashboard


505(b)(2) Clinical Trials for ARSENIC TRIOXIDE

This table shows clinical trials for potential 505(b)(2) applications. See the next table for all clinical trials
Trial Type Trial ID Title Status Sponsor Phase Start Date Summary
New Dosage NCT00225992 ↗ Phase II Research Study of Arsenic Trioxide (Trisenox) in Patients With Myelodysplastic Syndrome (MDS) Terminated Oncology Specialties, Alabama Phase 2 2004-02-01 In this phase II study besides evaluating for safety, the primary efficacy parameter is to evaluate the incidence of patients who have had a response to Trisenox by evidence of increased blood counts (red, white, or platelets) and/or by decrease or transfusion dependency. The secondary efficacy parameter is the assessment of the tolerability of the new dosing schedule. Arsenic trioxide will be administered intravenously over 1 to 2 hours with a loading dose of 0.30mg/kg for days 1-5 of the first week and then twice weekly for 27 weeks for a total of 28 weeks.
>Trial Type >Trial ID >Title >Status >Phase >Start Date >Summary

All Clinical Trials for ARSENIC TRIOXIDE

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00003395 ↗ Arsenic Trioxide in Treating Patients With Advanced Hematologic Cancer Completed National Cancer Institute (NCI) Phase 1 1998-04-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of arsenic trioxide in treating patients who have advanced hematologic cancer.
NCT00003395 ↗ Arsenic Trioxide in Treating Patients With Advanced Hematologic Cancer Completed Memorial Sloan Kettering Cancer Center Phase 1 1998-04-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of arsenic trioxide in treating patients who have advanced hematologic cancer.
NCT00003630 ↗ Arsenic Trioxide in Treating Patients With Advanced Solid Tumors Completed National Cancer Institute (NCI) Phase 1 1998-08-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of arsenic trioxide in treating patients who have advanced solid tumors.
NCT00003630 ↗ Arsenic Trioxide in Treating Patients With Advanced Solid Tumors Completed Memorial Sloan Kettering Cancer Center Phase 1 1998-08-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of arsenic trioxide in treating patients who have advanced solid tumors.
NCT00003885 ↗ Arsenic Trioxide in Treating Patients With Recurrent or Refractory Acute Leukemia, Chronic Myeloide Leukemia, Myelodysplasia, Lymphoma, or Myeloma Unknown status Our Lady of Mercy Medical Center Phase 2 1997-11-01 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of arsenic trioxide in treating patients who have recurrent or refractory acute leukemia, chronic myeloid leukemia, myelodysplasia, lymphoma, or myeloma.
NCT00003934 ↗ Tretinoin, Cytarabine, and Daunorubicin Hydrochloride With or Without Arsenic Trioxide Followed by Tretinoin With or Without Mercaptopurine and Methotrexate in Treating Patients With Acute Promyelocytic Leukemia Completed National Cancer Institute (NCI) Phase 3 1999-06-01 This randomized phase III trial is studying tretinoin and combination chemotherapy to see how well they work compared to tretinoin, combination chemotherapy, and arsenic trioxide in treating patients with acute promyelocytic leukemia that has not been treated previously. Drugs used in chemotherapy, such as daunorubicin, cytarabine, mercaptopurine, methotrexate, and arsenic trioxide, work in different ways to stop cancer cells from dividing so they stop growing or die. Tretinoin may help leukemia cells develop into normal white blood cells. It is not yet known which regimen is more effective for acute promyelocytic leukemia.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for ARSENIC TRIOXIDE

Condition Name

Condition Name for ARSENIC TRIOXIDE
Intervention Trials
Leukemia 31
Acute Promyelocytic Leukemia 15
Myelodysplastic Syndromes 13
Multiple Myeloma and Plasma Cell Neoplasm 9
[disabled in preview] 0
This preview shows a limited data set
Subscribe for full access, or try a Trial

Condition MeSH

Condition MeSH for ARSENIC TRIOXIDE
Intervention Trials
Leukemia 65
Leukemia, Promyelocytic, Acute 32
Leukemia, Myeloid 22
Myelodysplastic Syndromes 20
[disabled in preview] 0
This preview shows a limited data set
Subscribe for full access, or try a Trial

Clinical Trial Locations for ARSENIC TRIOXIDE

Trials by Country

Trials by Country for ARSENIC TRIOXIDE
Location Trials
United States 382
China 38
Canada 23
Italy 17
Spain 11
This preview shows a limited data set
Subscribe for full access, or try a Trial

Trials by US State

Trials by US State for ARSENIC TRIOXIDE
Location Trials
New York 31
California 26
Texas 23
Illinois 20
Ohio 14
This preview shows a limited data set
Subscribe for full access, or try a Trial

Clinical Trial Progress for ARSENIC TRIOXIDE

Clinical Trial Phase

Clinical Trial Phase for ARSENIC TRIOXIDE
Clinical Trial Phase Trials
Phase 4 6
Phase 3 12
Phase 2/Phase 3 3
[disabled in preview] 114
This preview shows a limited data set
Subscribe for full access, or try a Trial

Clinical Trial Status

Clinical Trial Status for ARSENIC TRIOXIDE
Clinical Trial Phase Trials
Completed 62
Terminated 26
Recruiting 23
[disabled in preview] 26
This preview shows a limited data set
Subscribe for full access, or try a Trial

Clinical Trial Sponsors for ARSENIC TRIOXIDE

Sponsor Name

Sponsor Name for ARSENIC TRIOXIDE
Sponsor Trials
National Cancer Institute (NCI) 52
Cephalon 13
Memorial Sloan Kettering Cancer Center 11
[disabled in preview] 23
This preview shows a limited data set
Subscribe for full access, or try a Trial

Sponsor Type

Sponsor Type for ARSENIC TRIOXIDE
Sponsor Trials
Other 193
NIH 54
Industry 45
[disabled in preview] 0
This preview shows a limited data set
Subscribe for full access, or try a Trial

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.