This study is to assess whether treatment with a therapeutic (100 mg) or supratherapeutic
(800 mg) dose of avanafil has the potential to cause QT/QTc prolongation in healthy
volunteers.
This study is to assess whether treatment with a therapeutic (100 mg) or supratherapeutic
(800 mg) dose of avanafil has the potential to cause QT/QTc prolongation in healthy
volunteers.
To Evaluate The Effect Of Ketoconazole, Ritonavir and Erythromycin on the Safety and Pharmacokinetics of Avanafil
Completed
VIVUS, Inc.
Phase 1
2008-10-01
This study is being conducted to examine the effect of three CYP3A4 inhibitors (ketoconazole,
erythromycin and ritonavir) on the single dose pharmacokinetics of avanafil. Ketoconazole and
ritonavir are potent inhibitors of CYP3A4 and erythromycin is a moderate CYP3A4 inhibitor.
Any interaction that is observed would be predictive of other inhibitors of CYP3A4.
Research Evaluating an Investigational Medication for Erectile Dysfunction - Diabetic ED (REVIVE-D)
Completed
VIVUS, Inc.
Phase 3
2008-12-01
This study is being conducted to compare the safety and efficacy of 2 doses of avanafil to
placebo in diabetic men with mild to severe erectile dysfunction.
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors.
Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data.
The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free.
thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user.
Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.
Alerts Available With Subscription
Alerts are available for users with active subscriptions.
