Effectiveness of Controlled-Release Morphine for Chronic Neuropathic Pain After Spinal Cord Injury
Completed
U.S. Department of Education
Phase 2
2007-07-01
We would like to learn if a medicine called "modified-release morphine sulfate" (Avinza)
helps reduce Spinal Cord Injury (SCI)-related pain that has lasted a long time.
"Modified-release" means that the medicine in the capsules is slowly released to the body,
instead of being released all at once. Avinza is approved by the Food and Drug Administration
for the treatment of pain, but we do not know how effective Avinza is in reducing SCI-related
pain.
Effectiveness of Controlled-Release Morphine for Chronic Neuropathic Pain After Spinal Cord Injury
Completed
Icahn School of Medicine at Mount Sinai
Phase 2
2007-07-01
We would like to learn if a medicine called "modified-release morphine sulfate" (Avinza)
helps reduce Spinal Cord Injury (SCI)-related pain that has lasted a long time.
"Modified-release" means that the medicine in the capsules is slowly released to the body,
instead of being released all at once. Avinza is approved by the Food and Drug Administration
for the treatment of pain, but we do not know how effective Avinza is in reducing SCI-related
pain.
Evaluation of Risk Minimization, Assessment and Outcomes in Patients With Chronic Pain Taking Avinza
Completed
Pfizer
Phase 4
2008-03-01
The purpose of this study is to provide information in a broad, "real world" population of
chronic pain patients assessing both pain control with AVINZA as well as the potential risk
for misuse and abuse.
Comparative Study to Evaluate KADIAN and Avinza in Healthy Adults
Completed
Actavis Inc.
Phase 4
2004-05-01
The primary objective of this study was to compare the single-dose relative bioavailability
of Alpharma Branded Products Division (Kadian®) and Ligand® Pharmaceuticals Inc. (AVINZA®) 30
mg morphine sulfate sustained-release capsules in healthy adult volunteers under fed
conditions.
The secondary objective of this study was to evaluate the adverse events associated with each
of these 2 different morphine sulfate modified-release commercial formulations
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