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Last Updated: November 18, 2024

CLINICAL TRIALS PROFILE FOR BELINOSTAT


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All Clinical Trials for BELINOSTAT

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00274651 ↗ A Phase II Clinical Trial of PXD101 in Patients With Recurrent or Refractory Cutaneous and Peripheral T-Cell Lymphomas Terminated Onxeo Phase 2 2006-01-01 Open-label, non-randomized trial to assess the effectiveness of PXD101 in patients with recurrent or refractory cutaneous or peripheral and other types of T-cell lymphomas. PXD101 is a new, potent histone deacetylase (HDAC) inhibitor. Patients are treated with belinostat(PXD101) 1000 mg/m2 on days 1-5 of a 21 day cycle.
NCT00301756 ↗ Belinostat in Treating Patients With Advanced Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer or Ovarian Low Malignant Potential Tumors Completed National Cancer Institute (NCI) Phase 2 2006-09-01 This phase II trial studies how well belinostat works in treating patients with ovarian epithelial cancer, primary peritoneal cancer, or fallopian tube cancer that have spread to other places in the body or ovarian low malignant potential tumors. Belinostat may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
NCT00303953 ↗ PXD101 in Treating Patients With Relapsed or Refractory Aggressive B-Cell Non-Hodgkin's Lymphoma Completed National Cancer Institute (NCI) Phase 2 2006-01-01 This phase II trial is studying how well PXD101 works in treating patients with relapsed or refractory aggressive B-cell non-Hodgkin's lymphoma. PXD101 may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the cancer.
NCT00321594 ↗ Belinostat in Treating Patients With Liver Cancer That Cannot Be Removed By Surgery Completed National Cancer Institute (NCI) Phase 1/Phase 2 2006-05-01 This phase I/II trial is studying the side effects and best dose of belinostat and to see how well it works in treating patients with liver cancer that cannot be removed by surgery. Belinostat may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth
NCT00334789 ↗ Belinostat and Isotretinoin in Treating Patients With Solid Tumors That Are Metastatic or That Cannot Be Removed by Surgery Completed National Cancer Institute (NCI) Phase 1 2006-06-12 This phase I trial is studying the side effects and best dose of belinostat when given together with isotretinoin in treating patients with metastatic or unresectable solid tumors. Belinostat may stop the growth of tumor cells by blocking blood flow to the tumor and by blocking some of the enzymes needed for cell growth. Isotretinoin may cause solid tumor cells to look more like normal cells, and to grow and spread more slowly. Giving belinostat together with isotretinoin may be an effective treatment for metastatic or unresectable solid tumors.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for BELINOSTAT

Condition Name

Condition Name for BELINOSTAT
Intervention Trials
Peripheral T-cell Lymphoma 4
Lymphoma 4
Recurrent Adult Diffuse Large Cell Lymphoma 4
Anaplastic Large Cell Lymphoma 3
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Condition MeSH

Condition MeSH for BELINOSTAT
Intervention Trials
Lymphoma 20
Lymphoma, T-Cell 13
Carcinoma 8
Leukemia 8
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Clinical Trial Locations for BELINOSTAT

Trials by Country

Trials by Country for BELINOSTAT
Location Trials
United States 174
Denmark 6
Canada 5
France 5
United Kingdom 5
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Trials by US State

Trials by US State for BELINOSTAT
Location Trials
California 14
Florida 12
Texas 11
Maryland 11
New York 10
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Clinical Trial Progress for BELINOSTAT

Clinical Trial Phase

Clinical Trial Phase for BELINOSTAT
Clinical Trial Phase Trials
Phase 3 3
Phase 2 17
Phase 1/Phase 2 8
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Clinical Trial Status

Clinical Trial Status for BELINOSTAT
Clinical Trial Phase Trials
Completed 27
Recruiting 10
Terminated 8
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Clinical Trial Sponsors for BELINOSTAT

Sponsor Name

Sponsor Name for BELINOSTAT
Sponsor Trials
National Cancer Institute (NCI) 24
Onxeo 11
Spectrum Pharmaceuticals, Inc 11
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Sponsor Type

Sponsor Type for BELINOSTAT
Sponsor Trials
Industry 42
Other 33
NIH 25
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