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Last Updated: November 22, 2024

CLINICAL TRIALS PROFILE FOR BUSULFEX


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All Clinical Trials for BUSULFEX

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00002831 ↗ Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Chronic Myelogenous or Acute Leukemia Completed National Cancer Institute (NCI) Phase 1/Phase 2 1995-08-01 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. PURPOSE: Phase I/II trial to study the effectiveness of high-dose chemotherapy plus peripheral stem cell transplantation in treating patients with chronic myelogenous or acute leukemia.
NCT00002831 ↗ Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Chronic Myelogenous or Acute Leukemia Completed M.D. Anderson Cancer Center Phase 1/Phase 2 1995-08-01 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. PURPOSE: Phase I/II trial to study the effectiveness of high-dose chemotherapy plus peripheral stem cell transplantation in treating patients with chronic myelogenous or acute leukemia.
NCT00003926 ↗ Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumors Terminated Masonic Cancer Center, University of Minnesota Phase 1 1998-11-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more tumor cells. Chemoprotective drugs such as amifostine may protect normal cells from the side effects of high-dose chemotherapy. PURPOSE: Phase I trial to study the effectiveness of amifostine in protecting from the side effects of peripheral stem cell transplantation in treating patients who have high-risk or relapsed solid tumors.
NCT00004088 ↗ Combination Chemo, Peripheral Stem Cell Transplant, Biological Therapy, Pamidronate and Thalidomide for Multiple Myeloma Completed National Cancer Institute (NCI) Phase 2 1999-04-13 RATIONALE: Drugs used in chemotherapy work in different ways to stop cancer cells from dividing so they stop growing or die. Peripheral stem cell transplantation may allow doctors to give higher doses of chemotherapy drugs and kill more cancer cells. Biological therapies, such as interferon alfa, use different ways to stimulate the immune system and stop cancer cells from growing. Thalidomide may stop the growth of cancer cells by stopping blood flow to the tumor. Pamidronate may help to reduce the side effects of treatment for multiple myeloma. PURPOSE: This phase II trial is studying combination chemotherapy, peripheral stem cell transplantation, biological therapy, pamidronate, and thalidomide to see how well they work in treating patients with stage I, stage II, or stage III multiple myeloma.
NCT00004088 ↗ Combination Chemo, Peripheral Stem Cell Transplant, Biological Therapy, Pamidronate and Thalidomide for Multiple Myeloma Completed City of Hope Medical Center Phase 2 1999-04-13 RATIONALE: Drugs used in chemotherapy work in different ways to stop cancer cells from dividing so they stop growing or die. Peripheral stem cell transplantation may allow doctors to give higher doses of chemotherapy drugs and kill more cancer cells. Biological therapies, such as interferon alfa, use different ways to stimulate the immune system and stop cancer cells from growing. Thalidomide may stop the growth of cancer cells by stopping blood flow to the tumor. Pamidronate may help to reduce the side effects of treatment for multiple myeloma. PURPOSE: This phase II trial is studying combination chemotherapy, peripheral stem cell transplantation, biological therapy, pamidronate, and thalidomide to see how well they work in treating patients with stage I, stage II, or stage III multiple myeloma.
NCT00014469 ↗ Combination Chemotherapy Followed by Bone Marrow Transplantation in Treating Patients With Advanced Hematologic Cancer Completed National Cancer Institute (NCI) Phase 2 2000-12-01 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with bone marrow transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of busulfan and melphalan followed by donor bone marrow transplantation in treating patients who have advanced hematologic cancer.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for BUSULFEX

Condition Name

Condition Name for BUSULFEX
Intervention Trials
Leukemia 33
Myelodysplastic Syndrome 25
Lymphoma 21
Acute Myeloid Leukemia 18
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Condition MeSH

Condition MeSH for BUSULFEX
Intervention Trials
Leukemia 62
Myelodysplastic Syndromes 41
Preleukemia 40
Leukemia, Myeloid 39
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Clinical Trial Locations for BUSULFEX

Trials by Country

Trials by Country for BUSULFEX
Location Trials
United States 311
Canada 19
Korea, Republic of 4
Israel 2
China 2
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Trials by US State

Trials by US State for BUSULFEX
Location Trials
Texas 54
New York 17
Minnesota 17
Massachusetts 15
California 13
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Clinical Trial Progress for BUSULFEX

Clinical Trial Phase

Clinical Trial Phase for BUSULFEX
Clinical Trial Phase Trials
Phase 3 8
Phase 2/Phase 3 5
Phase 2 79
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Clinical Trial Status

Clinical Trial Status for BUSULFEX
Clinical Trial Phase Trials
Completed 57
Recruiting 29
Terminated 24
[disabled in preview] 29
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Clinical Trial Sponsors for BUSULFEX

Sponsor Name

Sponsor Name for BUSULFEX
Sponsor Trials
M.D. Anderson Cancer Center 47
National Cancer Institute (NCI) 42
Masonic Cancer Center, University of Minnesota 14
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Sponsor Type

Sponsor Type for BUSULFEX
Sponsor Trials
Other 177
NIH 50
Industry 25
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