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Last Updated: November 2, 2024

CLINICAL TRIALS PROFILE FOR CARBOCAINE


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All Clinical Trials for CARBOCAINE

Trial ID Title Status Sponsor Phase Start Date Summary
NCT01981291 ↗ Duration of Sciatic Nerve Block After Injection of Local Anesthetic In or Around the Nerve Completed University of Parma Phase 4 2012-10-01 This study was designed to assess whether the injection of local anesthetic into the nerve (intraneural), as opposed to around it (perineural), leads to longer anesthesia and analgesia of the leg. Some reports of accidental intraneural injection mention an extremely long duration. When different drugs and doses were evaluated in a clinical trial of intraneural injection, a longer-than-expected duration was reported. The investigators will compare the two types of injection using the same drug, so as to determine if there is an actual difference in duration.
NCT02384915 ↗ Spinal Anesthesia Versus Combined Sciatic-femoral Nerve Block for Outpatient Knee Arthroscopy Completed ASST Gaetano Pini-CTO Phase 4 2015-01-01 The aim of the study is to compare the time of home discharge in day-case patients receiving either a spinal anesthesia or a combined sciatic-femoral nerve block for knee arthroscopy
NCT02829697 ↗ The Effect of Local Anaesthetic Volume on Nerve Block Duration and Nerve Block Duration Variability Completed Innovation Fund Denmark Phase 4 2016-07-01 The aim is to investigate the effect of perineural administration of a series of different volumes of local anaesthesia (ropivacaine 0.2%) on nerve block duration and the variability of the duration in the common peroneal nerve and the sciatic nerve in healthy volunteers. The hypothesis is that nerve block duration is correlated to local anaesthetic volume, but only to a certain degree. After a sufficient volume a 'saturation level' will be reached, and nerve block duration will not increase further.
NCT02829697 ↗ The Effect of Local Anaesthetic Volume on Nerve Block Duration and Nerve Block Duration Variability Completed Nordsjaellands Hospital Phase 4 2016-07-01 The aim is to investigate the effect of perineural administration of a series of different volumes of local anaesthesia (ropivacaine 0.2%) on nerve block duration and the variability of the duration in the common peroneal nerve and the sciatic nerve in healthy volunteers. The hypothesis is that nerve block duration is correlated to local anaesthetic volume, but only to a certain degree. After a sufficient volume a 'saturation level' will be reached, and nerve block duration will not increase further.
NCT03390426 ↗ Femoral Peri-arterial Local Anesthetic Injection Decreases Tourniquet Associated Ischemic Hypertension Completed Duke University Phase 4 2018-05-03 The purpose of this prospective randomized double-blind study is to determine if the novel technique of ultrasound guided peri-arterial injection of local anesthetic around the femoral artery decreases ischemic hypertension associated with prolonged lower extremity tourniquet time during total ankle arthroplasty (TAA) and foot fusion surgeries. Patients will be randomized 1:1 to receive either local anesthetic or saline, which will be injected superomedially to the femoral artery in an attempt to block sympathetic afferents and decrease tourniquet associated hypertension intraoperatively.
NCT04454203 ↗ Femoral Peri-arterial Local Anesthetic Injection Via Peri-arterial Perineural Catheter Reverses Tourniquet Associated Ischemic Hypertension Recruiting Duke University Phase 4 2021-02-05 The goal of this prospective randomized double-blind study is to determine if an ultrasound guided peri-arterial injection of local anesthetic (LA) superomedially the femoral artery via peripheral nerve catheter reverses ischemic hypertension associated with prolonged lower extremity tourniquet time.
NCT06047366 ↗ Combination of Buffered Anesthetic to Treat Mandibular Molars Recruiting Indiana University Phase 4 2023-12-05 The purpose of this study is to determine whether a combination of anesthetics (numbing medicine) will adequately anesthetize teeth over a different combination. A second purpose is to see if the time needed to numb the nerve in a tooth is different between the two anesthetics.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for CARBOCAINE

Condition Name

Condition Name for CARBOCAINE
Intervention Trials
Ankle Fusion 2
Intraoperative Hypertension 2
Postoperative Pain 2
Total Ankle Arthroplasty 2
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Condition MeSH

Condition MeSH for CARBOCAINE
Intervention Trials
Hypertension 2
Pain, Postoperative 2
Arthritis 1
Pulpitis 1
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Clinical Trial Locations for CARBOCAINE

Trials by Country

Trials by Country for CARBOCAINE
Location Trials
United States 3
Italy 2
Denmark 1
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Trials by US State

Trials by US State for CARBOCAINE
Location Trials
North Carolina 2
Indiana 1
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Clinical Trial Progress for CARBOCAINE

Clinical Trial Phase

Clinical Trial Phase for CARBOCAINE
Clinical Trial Phase Trials
Phase 4 6
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Clinical Trial Status

Clinical Trial Status for CARBOCAINE
Clinical Trial Phase Trials
Completed 4
Recruiting 2
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Clinical Trial Sponsors for CARBOCAINE

Sponsor Name

Sponsor Name for CARBOCAINE
Sponsor Trials
Duke University 2
University of Parma 1
ASST Gaetano Pini-CTO 1
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Sponsor Type

Sponsor Type for CARBOCAINE
Sponsor Trials
Other 7
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