Motexafin Gadolinium With MRI-Guided Surgery in Treating Patients With High-Grade Gliomas
Completed
National Cancer Institute (NCI)
Phase 1
1998-07-01
RATIONALE: New imaging procedures such as the use of gadolinium texaphyrin with MRI may
improve the ability to detect the extent of gliomas.
PURPOSE: Phase I trial to study the effectiveness of gadolinium texaphyrin used with
MRI-guided surgery in treating patients with high-grade glioma.
Motexafin Gadolinium With MRI-Guided Surgery in Treating Patients With High-Grade Gliomas
Completed
Jonsson Comprehensive Cancer Center
Phase 1
1998-07-01
RATIONALE: New imaging procedures such as the use of gadolinium texaphyrin with MRI may
improve the ability to detect the extent of gliomas.
PURPOSE: Phase I trial to study the effectiveness of gadolinium texaphyrin used with
MRI-guided surgery in treating patients with high-grade glioma.
Randomized Study of the Use of Intravenous Choline Supplementation in Long Term Total Parenteral Nutrition
Completed
University of Texas
N/A
1997-11-01
OBJECTIVES:
I. Determine whether intravenous choline supplementation will reverse the hepatic steatosis
and improve liver function in patients who receive long term total parenteral nutrition.
Study of Phosphatidylcholine in a Patient With Methionine Adenosyltransferase Deficiency
Completed
UNC Lineberger Comprehensive Cancer Center
N/A
2000-01-01
OBJECTIVES: I. Determine whether plasma choline and breast milk choline levels are low at
fasting in a patient with methionine adenosyltransferase deficiency, and if the choline
levels are low, determine whether choline levels respond to dietary supplementation with
phosphatidylcholine.
II. Determine whether this patient has a fatty liver by magnetic resonance spectroscopy.
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