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Last Updated: December 22, 2024

CLINICAL TRIALS PROFILE FOR CLADRIBINE

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All Clinical Trials for CLADRIBINE

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Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00002805 ↗	Combination Chemotherapy in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome	Completed	National Cancer Institute (NCI)	Phase 2	1997-08-01	RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy in treating patients with acute myeloid leukemia or myelodysplastic syndrome in first relapse or who did not achieve first remission.
NCT00002805 ↗	Combination Chemotherapy in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome	Completed	Children's Oncology Group	Phase 2	1997-08-01	RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy in treating patients with acute myeloid leukemia or myelodysplastic syndrome in first relapse or who did not achieve first remission.
NCT00002833 ↗	Peripheral Stem Cell Transplantation Plus Filgrastim in Treating Patients With Acute or Chronic Myelogenous Leukemia	Completed	National Cancer Institute (NCI)	Phase 2	1994-10-01	RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. Colony stimulating factors such as filgrastim may increase the number of immune cells found in bone marrow or peripheral blood and may help a person's immune system recover from the side effects of chemotherapy. PURPOSE: Phase II trial to study the effectiveness of peripheral stem cell transplantation plus filgrastim in treating patients who have acute or chronic myelogenous leukemia.
NCT00002833 ↗	Peripheral Stem Cell Transplantation Plus Filgrastim in Treating Patients With Acute or Chronic Myelogenous Leukemia	Completed	M.D. Anderson Cancer Center	Phase 2	1994-10-01	RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. Colony stimulating factors such as filgrastim may increase the number of immune cells found in bone marrow or peripheral blood and may help a person's immune system recover from the side effects of chemotherapy. PURPOSE: Phase II trial to study the effectiveness of peripheral stem cell transplantation plus filgrastim in treating patients who have acute or chronic myelogenous leukemia.
NCT00002879 ↗	Cladribine in Patients With Mantle Cell Lymphoma	Completed	National Cancer Institute (NCI)	Phase 2	1996-11-01	RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effects of cladribine in previously treated or untreated patients with mantle cell lymphoma.
NCT00002879 ↗	Cladribine in Patients With Mantle Cell Lymphoma	Completed	Alliance for Clinical Trials in Oncology	Phase 2	1996-11-01	RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effects of cladribine in previously treated or untreated patients with mantle cell lymphoma.
NCT00003174 ↗	Bryostatin 1 Plus Cladribine in Treating Patients With Relapsed Chronic Lymphocytic Leukemia	Completed	National Cancer Institute (NCI)	Phase 1	1998-05-01	RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: This phase I trial is studying the side effects and best dose of cladribine when given with bryostatin 1 in treating patients with relapsed chronic lymphocytic leukemia.
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Start Date	>Summary

Clinical Trial Conditions for CLADRIBINE

Condition Name

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Condition Name for CLADRIBINE
Intervention	Trials
Acute Myeloid Leukemia	27
Leukemia	19
Multiple Sclerosis	13
Lymphoma	9
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Condition MeSH

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Condition MeSH for CLADRIBINE
Intervention	Trials
Leukemia	78
Leukemia, Myeloid	52
Leukemia, Myeloid, Acute	52
Lymphoma	21
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Clinical Trial Locations for CLADRIBINE

Trials by Country

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Trials by Country for CLADRIBINE
Location	Trials
United States	240
China	38
Canada	18
Germany	16
Poland	14
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Trials by US State

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Trials by US State for CLADRIBINE
Location	Trials
Texas	22
Washington	16
New York	10
Maryland	10
California	10
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Clinical Trial Progress for CLADRIBINE

Clinical Trial Phase

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Clinical Trial Phase for CLADRIBINE
Clinical Trial Phase	Trials
Phase 4	11
Phase 3	16
Phase 2/Phase 3	7
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Clinical Trial Status

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Clinical Trial Status for CLADRIBINE
Clinical Trial Phase	Trials
Recruiting	50
Completed	43
Unknown status	13
[disabled in preview]	27
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Clinical Trial Sponsors for CLADRIBINE

Sponsor Name

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Sponsor Name for CLADRIBINE
Sponsor	Trials
National Cancer Institute (NCI)	33
M.D. Anderson Cancer Center	16
EMD Serono	8
[disabled in preview]	22
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Sponsor Type

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Sponsor Type for CLADRIBINE
Sponsor	Trials
Other	195
Industry	46
NIH	34
[disabled in preview]	1
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