CLINICAL TRIALS PROFILE FOR CLEVIDIPINE
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All Clinical Trials for CLEVIDIPINE
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT00093249 ↗ | Study of Clevidipine Assessing Its Preoperative Antihypertensive Effect in Cardiac Surgery (ESCAPE-1) | Completed | The Medicines Company | Phase 3 | 2004-01-01 | The purpose of this study is to determine the efficacy of clevidipine injection versus placebo in treating preoperative hypertension. |
| NCT00093262 ↗ | Study of Clevidipine Assessing Its Postoperative Antihypertensive Effect in Cardiac Surgery (ESCAPE-2) | Completed | The Medicines Company | Phase 3 | 2003-12-01 | The purpose of this study is to establish the efficacy of of clevidipine versus placebo in treating postoperative hypertension. Approximately 100 patients with postoperative hypertension undergoing coronary artery bypass grafting (CABG), off-pump coronary artery bypass (OPCAB) or minimally invasive direct coronary artery bypass (MIDCAB) surgery and/or valve replacement/repair procedures were anticipated to be randomly assigned to one of two treatment groups: clevidipine or placebo. |
| NCT00093886 ↗ | Clevidipine in the Perioperative Treatment of Hypertension (ECLIPSE-NTG) | Completed | The Medicines Company | Phase 3 | 2004-04-01 | The purpose of this study is to establish the safety of clevidipine in the treatment of perioperative hypertension. Approximately 500-900 patients with perioperative hypertension undergoing coronary artery bypass grafting (CABG), off-pump coronary artery bypass (OPCAB) or minimally invasive direct coronary artery bypass (MIDCAB) surgery and/or valve replacement/repair procedures were anticipated to be randomly assigned to one of two treatment groups: clevidipine or nitroglycerin. |
| NCT00093912 ↗ | Clevidipine in the Perioperative Treatment of Hypertension (ECLISPE-SNP) | Completed | The Medicines Company | Phase 3 | 2004-06-01 | The purpose of this study is to establish the safety of clevidipine in the treatment of perioperative hypertension. Approximately 250-500 patients with perioperative hypertension undergoing coronary artery bypass grafting (CABG), off-pump coronary artery bypass (OPCAB) or minimally invasive direct coronary artery bypass (MIDCAB) surgery and/or valve replacement/repair procedures were anticipated to be randomly assigned to one of two treatment groups: clevidipine or sodium nitroprusside. |
| NCT00093925 ↗ | Clevidipine in the Postoperative Treatment of Hypertension (ECLIPSE-NIC) | Completed | The Medicines Company | Phase 3 | 2004-05-01 | The purpose of this study is to establish the safety of clevidipine in the treatment of postoperative hypertension. Approximately 250-500 patients with postoperative hypertension after undergoing coronary artery bypass grafting (CABG), off-pump coronary artery bypass (OPCAB) or minimally invasive direct coronary artery bypass (MIDCAB) surgery and/or valve replacement/repair procedures were anticipated to be randomly assigned to one of two treatment groups: clevidipine or nicardipine. |
| NCT00369837 ↗ | Clevidipine in the Treatment of Patients With Severe Hypertension (VELOCITY) | Completed | The Medicines Company | Phase 3 | 2006-09-01 | The purpose of this study was to determine the safety of clevidipine for treating severely elevated blood pressure, defined as systolic (SBP) >180 mmHg and/or diastolic blood pressure (DBP) >115 mmHg assessed on 2 successive occasions 15 minutes apart at baseline, in patients with or without major organ injury, particularly with respect to controlled dose adjustment to desired effect and prolonged continuous infusion. Enrollment of patients into the study was to continue until the target goal of 100 patients with at least 18 hours of continuous clevidipine treatment, including a minimum of 50 patients with acute or chronic end-organ injury, was met. |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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