CLINICAL TRIALS PROFILE FOR COGENTIN
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All Clinical Trials for COGENTIN
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT00018200 ↗ | Effect of Antidepressants on Back Pain | Completed | US Department of Veterans Affairs | Phase 2 | 1999-04-01 | The purpose of this study is to determine whether different types of antidepressant medicines relieve back pain that has lasted at least six months on a daily basis. Study participants will be assigned to treatment with either a antidepressant acting on the serotonin system in the brain (fluoxetine), one acting on the noradrenaline system (desipramine, or to a control medication not expected to relieve pain (benztropine). Each participant will be seen at least nine times during their 12 weeks on medication. This is a phase 2/3, outpatient study. |
| NCT00018200 ↗ | Effect of Antidepressants on Back Pain | Completed | VA Office of Research and Development | Phase 2 | 1999-04-01 | The purpose of this study is to determine whether different types of antidepressant medicines relieve back pain that has lasted at least six months on a daily basis. Study participants will be assigned to treatment with either a antidepressant acting on the serotonin system in the brain (fluoxetine), one acting on the noradrenaline system (desipramine, or to a control medication not expected to relieve pain (benztropine). Each participant will be seen at least nine times during their 12 weeks on medication. This is a phase 2/3, outpatient study. |
| NCT00457366 ↗ | A Comparison Study of the Efficacy of Quetiapine and Haloperidol in Agitated Adults in Emergency Room | Completed | AstraZeneca | Phase 4 | 2006-05-01 | In the Psychiatric Emergency Room, agitated patients are treated routinely with an I.M. Haloperidol "cocktail" (Haloperidol 5 mg, Lorazepam 2 mg, Cogentin 2 mg), which has proved to be an effective treatment. However, since it is an intramuscular injection, it is more complicated and perhaps less acceptable to patients as well as more likely to cause EPS (extrapyramidal symptoms). Of late in our emergency room, we started using high dose Quetiapine 300 mg PO to replace the "cocktail" for treating agitation. It has shown promising results. |
| NCT00457366 ↗ | A Comparison Study of the Efficacy of Quetiapine and Haloperidol in Agitated Adults in Emergency Room | Completed | University of Southern California | Phase 4 | 2006-05-01 | In the Psychiatric Emergency Room, agitated patients are treated routinely with an I.M. Haloperidol "cocktail" (Haloperidol 5 mg, Lorazepam 2 mg, Cogentin 2 mg), which has proved to be an effective treatment. However, since it is an intramuscular injection, it is more complicated and perhaps less acceptable to patients as well as more likely to cause EPS (extrapyramidal symptoms). Of late in our emergency room, we started using high dose Quetiapine 300 mg PO to replace the "cocktail" for treating agitation. It has shown promising results. |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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