CLINICAL TRIALS PROFILE FOR COLGATE TOTAL

All Clinical Trials for COLGATE TOTAL

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT01300780 ↗	Effect of an Anti-inflammatory on Tooth Sensitivity Caused by Bleaching	Completed	Fundação Araucária	N/A	2010-04-01	Perhaps the use of a more selective anti-inflammatory drug, capable of inhibiting enzyme specific for pain may be more effective in preventing the tooth sensitivity caused by the inflammatory response produced by in-office bleaching. To the extent of the authors´ knowledge, no study has so far addressed the use of a selective anti-inflammatory drug specific for pain enzyme on tooth sensitivity, being this the aim of the present investigation.
NCT01300780 ↗	Effect of an Anti-inflammatory on Tooth Sensitivity Caused by Bleaching	Completed	Universidade Estadual de Ponta Grossa	N/A	2010-04-01	Perhaps the use of a more selective anti-inflammatory drug, capable of inhibiting enzyme specific for pain may be more effective in preventing the tooth sensitivity caused by the inflammatory response produced by in-office bleaching. To the extent of the authors´ knowledge, no study has so far addressed the use of a selective anti-inflammatory drug specific for pain enzyme on tooth sensitivity, being this the aim of the present investigation.
NCT01300780 ↗	Effect of an Anti-inflammatory on Tooth Sensitivity Caused by Bleaching	Completed	Eloisa Andrade de Paula	N/A	2010-04-01	Perhaps the use of a more selective anti-inflammatory drug, capable of inhibiting enzyme specific for pain may be more effective in preventing the tooth sensitivity caused by the inflammatory response produced by in-office bleaching. To the extent of the authors´ knowledge, no study has so far addressed the use of a selective anti-inflammatory drug specific for pain enzyme on tooth sensitivity, being this the aim of the present investigation.
NCT01837199 ↗	MTZ Plus AMX in the Treatment of Smokers and Non-smokers	Completed	University of Guarulhos	Phase 4	2011-07-01	Randomized controlled clinical trials have demonstrated that the use of amoxicillin (AMX) and metronidazole (MTZ) as adjuncts to mechanical therapy improves the clinical and microbiological outcomes of scaling and root planing (SRP) in non-smokers and smokers with ChP. However, the effects of this antibiotic protocol have not been directly compared in non-smokers and smokers. Therefore, the aim of this study will be to compare the clinical and microbiological effects of the adjunctive use of MTZ+AMX to SRP in smokers and non-smokers subjects with chronic periodontitis (ChP). It was hypothesized that non-smokers would benefit better from this combination of therapies than the smokers.
NCT01881074 ↗	Periodontal Treatment Response in Type II Diabetic Patients	Completed	Colgate Palmolive		2012-06-01	Diabetes mellitus affects > 171 million people worldwide, with type II diabetes being the most prevalent, affecting 85-95% of the diabetic population. Unfortunately, despite conventional medical treatment, some diabetic patients do not seem to be able to reach desirable metabolic control. This is a double-blinded, randomized study investigating the effects of triclosan containing toothpaste (commercial name: Colgate Total) on the response to periodontal treatment in type II diabetic patients with periodontal disease. The investigators believe that using triclosan containing toothpaste during periodontal treatment will decrease the local inflammatory response and that this reduction will improve periodontal status and metabolic control.
NCT01881074 ↗	Periodontal Treatment Response in Type II Diabetic Patients	Completed	University of Florida		2012-06-01	Diabetes mellitus affects > 171 million people worldwide, with type II diabetes being the most prevalent, affecting 85-95% of the diabetic population. Unfortunately, despite conventional medical treatment, some diabetic patients do not seem to be able to reach desirable metabolic control. This is a double-blinded, randomized study investigating the effects of triclosan containing toothpaste (commercial name: Colgate Total) on the response to periodontal treatment in type II diabetic patients with periodontal disease. The investigators believe that using triclosan containing toothpaste during periodontal treatment will decrease the local inflammatory response and that this reduction will improve periodontal status and metabolic control.
NCT02080273 ↗	Six Month Plaque and Gingivitis Study Using Colgate Total Toothpaste	Completed	Mahidol University	Phase 4	2013-03-01	The objective of this randomized, single center, parallel clinical research study is to evaluate the comparative efficacy performance of three dentifrices -Colgate Total Toothpaste, Parodontax Toothpaste and Colgate Cavity Protection Toothpaste in controlling gingivitis and dental plaque in adults.

Clinical Trial Conditions for COLGATE TOTAL

Condition Name

Condition Name for COLGATE TOTAL
Intervention	Trials
Gingivitis	5
Dental Plaque	3
Covid19	2
Oral Hygiene	2

Condition MeSH

Condition MeSH for COLGATE TOTAL
Intervention	Trials
Gingivitis	8
Hypersensitivity	6
Dentin Sensitivity	6
Dental Plaque	4

Clinical Trial Locations for COLGATE TOTAL

Trials by Country

Trials by Country for COLGATE TOTAL
Location	Trials
United States	8
Brazil	6
Iraq	3
Pakistan	2
India	2

Trials by US State

Trials by US State for COLGATE TOTAL
Location	Trials
North Carolina	2
California	2
Florida	2
New Jersey	1
Indiana	1

Clinical Trial Progress for COLGATE TOTAL

Clinical Trial Phase

Clinical Trial Phase for COLGATE TOTAL
Clinical Trial Phase	Trials
Phase 4	10
Phase 3	6
Phase 2/Phase 3	2

Clinical Trial Status

Clinical Trial Status for COLGATE TOTAL
Clinical Trial Phase	Trials
Completed	22
Not yet recruiting	4
Recruiting	2

Clinical Trial Sponsors for COLGATE TOTAL

Sponsor Name

Sponsor Name for COLGATE TOTAL
Sponsor	Trials
Colgate Palmolive	12
University of North Carolina, Chapel Hill	2
University of Campinas, Brazil	2

Sponsor Type

Sponsor Type for COLGATE TOTAL
Sponsor	Trials
Other	28
Industry	13