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Last Updated: December 22, 2024

CLINICAL TRIALS PROFILE FOR COSOPT

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All Clinical Trials for COSOPT

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Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00140049 ↗	A 12week, Randomized, Evaluator-Masked, Parallel Group Comparing Evening Dosing Of Xalacom Vs Cosopt In Subj W/ Glaucoma	Completed	Pfizer	Phase 4	2005-07-01	To demonstrate the statistical non inferiority of the combination of latanoprost and timolol given in the evening time once a day vs the combination of dorzamalide and timolol twice a day based on intraocular pressure measurements at 8 AM, 12 noon & 4 PM during a 12 week treatment.
NCT00140049 ↗	A 12week, Randomized, Evaluator-Masked, Parallel Group Comparing Evening Dosing Of Xalacom Vs Cosopt In Subj W/ Glaucoma	Completed	Pfizer's Upjohn has merged with Mylan to form Viatris Inc.	Phase 4	2005-07-01	To demonstrate the statistical non inferiority of the combination of latanoprost and timolol given in the evening time once a day vs the combination of dorzamalide and timolol twice a day based on intraocular pressure measurements at 8 AM, 12 noon & 4 PM during a 12 week treatment.
NCT00273429 ↗	Cosopt Versus Xalatan	Completed	Pharmaceutical Research Network	Phase 4	2005-04-01	To compare the 24-hour efficacy and safety, measured every three hours, of the dorzolamide/timolol fixed combination given twice daily versus latanoprost and placebo each given once daily.
NCT00273442 ↗	Assessing Cosopt Switch Patients	Completed	Pharmaceutical Research Network	Phase 4	2005-11-01	To assess the safety and efficacy of a cohort of patients switched to the dorzolamide/timolol maleate fixed combination because they are insufficiently controlled on latanoprost monotherapy.
NCT00273455 ↗	Lumigan Versus Cosopt	Completed	Pharmaceutical Research Network	Phase 4	2006-01-01	To compare the intraocular pressure effect and safety of the dorzolamide/timolol fixed combination given twice daily versus bimatoprost given once every evening in patients with open-angle glaucoma in patients insufficiently controlled on latanoprost monotherapy
NCT00273481 ↗	Cosopt Versus Xalacom	Completed	Pharmaceutical Research Network	Phase 4	2005-09-01	To compare the intraocular pressure efficacy and safety of the DTFC given twice daily versus the LTFC given once every morning following a run-in period with timolol maleate given twice daily.
NCT00314171 ↗	A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension	Completed	Alcon Research	Phase 3	2005-10-01	The purpose of this study is to determine whether a glaucoma therapy is safe and effective in treating patients with open-angle glaucoma or ocular hypertension.
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Start Date	>Summary

Clinical Trial Conditions for COSOPT

Condition Name

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Condition Name for COSOPT
Intervention	Trials
Ocular Hypertension	19
Glaucoma	15
Open-angle Glaucoma	10
Wet Macular Degeneration	2
[disabled in preview]	0
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Condition MeSH

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Condition MeSH for COSOPT
Intervention	Trials
Glaucoma	27
Ocular Hypertension	20
Glaucoma, Open-Angle	15
Hypertension	15
[disabled in preview]	0
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Clinical Trial Locations for COSOPT

Trials by Country

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Trials by Country for COSOPT
Location	Trials
United States	23
Canada	4
Greece	3
Italy	2
Mexico	2
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Trials by US State

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Trials by US State for COSOPT
Location	Trials
Pennsylvania	3
Massachusetts	3
Illinois	2
Michigan	2
Indiana	2
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Clinical Trial Progress for COSOPT

Clinical Trial Phase

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Clinical Trial Phase for COSOPT
Clinical Trial Phase	Trials
Phase 4	18
Phase 3	5
Phase 2/Phase 3	1
[disabled in preview]	10
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Clinical Trial Status

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Clinical Trial Status for COSOPT
Clinical Trial Phase	Trials
Completed	28
Unknown status	4
Terminated	2
[disabled in preview]	1
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Clinical Trial Sponsors for COSOPT

Sponsor Name

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Sponsor Name for COSOPT
Sponsor	Trials
Alcon Research	9
Merck Sharp & Dohme Corp.	6
Pharmaceutical Research Network	4
[disabled in preview]	9
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Sponsor Type

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Sponsor Type for COSOPT
Sponsor	Trials
Other	24
Industry	23
[disabled in preview]	0
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