A Phase II Trial of Early Medical Adrenalectomy for "D0.5" Prostate Cancer
Terminated
Janssen Pharmaceuticals
Phase 2
2000-05-01
RATIONALE: Androgens can stimulate the growth of prostate cancer cells. Drugs such as
aminoglutethimide or ketoconazole may stop the adrenal glands from producing hormones.
Combining hydrocortisone with either aminoglutethimide or ketoconazole may be an effective
treatment for prostate cancer.
PURPOSE: Phase II trial to study the effectiveness of combining hydrocortisone with either
aminoglutethimide or ketoconazole in treating patients who have localized stage IV prostate
cancer.
A Phase II Trial of Early Medical Adrenalectomy for "D0.5" Prostate Cancer
Terminated
National Cancer Institute (NCI)
Phase 2
2000-05-01
RATIONALE: Androgens can stimulate the growth of prostate cancer cells. Drugs such as
aminoglutethimide or ketoconazole may stop the adrenal glands from producing hormones.
Combining hydrocortisone with either aminoglutethimide or ketoconazole may be an effective
treatment for prostate cancer.
PURPOSE: Phase II trial to study the effectiveness of combining hydrocortisone with either
aminoglutethimide or ketoconazole in treating patients who have localized stage IV prostate
cancer.
A Phase II Trial of Early Medical Adrenalectomy for "D0.5" Prostate Cancer
Terminated
H. Lee Moffitt Cancer Center and Research Institute
Phase 2
2000-05-01
RATIONALE: Androgens can stimulate the growth of prostate cancer cells. Drugs such as
aminoglutethimide or ketoconazole may stop the adrenal glands from producing hormones.
Combining hydrocortisone with either aminoglutethimide or ketoconazole may be an effective
treatment for prostate cancer.
PURPOSE: Phase II trial to study the effectiveness of combining hydrocortisone with either
aminoglutethimide or ketoconazole in treating patients who have localized stage IV prostate
cancer.
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