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Last Updated: November 24, 2024

CLINICAL TRIALS PROFILE FOR DESLORATADINE


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All Clinical Trials for DESLORATADINE

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00160537 ↗ POPULAR (Preference Of Patient Using Levocetirizine in Allergic Rhinitis) Completed UCB Pharma Phase 4 2005-05-01 Comparative study on clinical efficacy and safety of levocetirizine and desloratadine as measured by the subject's satisfaction/dissatisfaction after one week of treatment
NCT00160589 ↗ LEADER (LEvocetirizine And DEsloratadine in Allergic Rhinitis) Completed UCB Pharma Phase 4 2005-04-01 Two weeks study to evaluate the efficacy and safety of Levocetirizine and Desloratadine in patients suffering from Allergic Rhinitis (AR)
NCT00264303 ↗ CUTE (Chronic Urticaria Treatment Evaluation) Completed UCB Pharma Phase 4 2005-12-01 A study to compare the clinical efficacy and safety of Levocetirizine vs. Desloratadine in patients suffering from Chronic Idiopathic Urticaria (CIU) measured by the mean pruritus severity score over the first week of treatment
NCT00311844 ↗ A Study of the Effects of Desloratadine on Conjunctival Allergen Challenge-induced Ocular Signs and Symptoms (Study P04209) Completed Merck Sharp & Dohme Corp. Phase 4 2005-03-01 This study was a double-blind, placebo-controlled, cross-over, single-center study of desloratadine 5 mg or placebo in subjects 18 years of age or older with a history of seasonal allergic rhinoconjunctivitis. This study was performed to examine the effects of desloratadine compared with placebo, on the signs and symptoms of allergic conjunctivitis induced by direct conjunctival challenges with a previously identified sensitizing antigen, in the eyes of a subject known to be sensitive to the antigen.
NCT00346606 ↗ The Efficacy and Safety of Desloratadine With Levocetirizine in Treatment of Chronic Idiopathic Urticaria Unknown status Lotus Pharmaceutical Phase 4 2006-01-01 Objective: To compare the efficacy of desloratadine 5mg (Denosin®) and levocetirizine 5mg (Xyzal®) once daily in the treatment of patients with CIU over 6 weeks. Trial design: Randomized, Double-Blind, Active-Controlled, Parallel-Group Study. Primary end point: To evaluate the change in average AM/PM reflective pruritus score from baseline recorded in the subjects' diaries during the first two weeks of the treatment. Secondary Objectives: To assess the efficacy and safety of desloratadine 5mg (Denosin®) and levocetirizine 5mg (Xyzal®) once daily in the treatment of subjects with CIU over 6 weeks.
NCT00359138 ↗ The Duration of the Suppressive Effects of Desloratadine on Allergen Prick Tests After Discontinuation (P04441) Completed Merck Sharp & Dohme Corp. Phase 4 2006-02-01 This is a randomized, double-blind, double-dummy, placebo-controlled, parallel-group, single center study in subjects with positive histamine skin prick test and a positive RadioAllergoSorbent Test (RAST) (class > 2) to one of the tested standardized allergenic extracts: tree pollen, cat dander, house dust mite, or a mixture of five grass pollens. Subjects will be randomized to desloratadine 5 mg once daily, levocetirizine 5mg once daily, or placebo once daily for 8 days of treatment followed by 11 days of skin testing after discontinuation of the antihistamine treatment phase. The duration of the suppressive effects of desloratadine on cutaneous allergen-induced wheal and flare responses after discontinuation of a one-week treatment will be established.
NCT00405964 ↗ Study for the Treatment of Persistent Allergic Rhinitis With Desloratadine (Study P04684) Completed Merck Sharp & Dohme Corp. Phase 3 2006-09-01 This study will investigate the effectiveness of desloratadine in treating subjects with allergic rhinitis who meet the criteria for persistent allergic rhinitis (PER)
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for DESLORATADINE

Condition Name

Condition Name for DESLORATADINE
Intervention Trials
Urticaria 12
Allergic Rhinitis 10
Seasonal Allergic Rhinitis 9
Chronic Idiopathic Urticaria 5
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Condition MeSH

Condition MeSH for DESLORATADINE
Intervention Trials
Rhinitis 28
Rhinitis, Allergic 27
Urticaria 19
Rhinitis, Allergic, Seasonal 13
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Clinical Trial Locations for DESLORATADINE

Trials by Country

Trials by Country for DESLORATADINE
Location Trials
United States 8
Germany 6
Canada 5
Brazil 5
China 3
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Trials by US State

Trials by US State for DESLORATADINE
Location Trials
Florida 5
New Jersey 2
Maryland 1
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Clinical Trial Progress for DESLORATADINE

Clinical Trial Phase

Clinical Trial Phase for DESLORATADINE
Clinical Trial Phase Trials
Phase 4 26
Phase 3 22
Phase 2/Phase 3 1
[disabled in preview] 15
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Clinical Trial Status

Clinical Trial Status for DESLORATADINE
Clinical Trial Phase Trials
Completed 58
Unknown status 3
Terminated 3
[disabled in preview] 4
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Clinical Trial Sponsors for DESLORATADINE

Sponsor Name

Sponsor Name for DESLORATADINE
Sponsor Trials
Merck Sharp & Dohme Corp. 32
Dr. Reddy's Laboratories Limited 6
UCB Pharma 4
[disabled in preview] 9
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Sponsor Type

Sponsor Type for DESLORATADINE
Sponsor Trials
Industry 56
Other 15
NIH 1
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