CLINICAL TRIALS PROFILE FOR DEXACEN-4
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All Clinical Trials for DEXACEN-4
Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
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NCT03031730 ↗ | Testing the Addition of KRT-232 (AMG 232) to Usual Chemotherapy for Relapsed Multiple Myeloma | Recruiting | National Cancer Institute (NCI) | Phase 1 | 2017-10-27 | This phase I trial studies the side effects and best dose of MDM2 Inhibitor KRT-232 when given together with carfilzomib, lenalidomide, and dexamethasone in treating patient with multiple myeloma that has come back (relapsed) or has not responded to previous treatment (refractory). KRT-232 (AMG 232) may stop the growth of cancer cells by blocking a protein called MDM2 that is needed for cell growth. Lenalidomide help shrink or slow the growth of multiple myeloma. Drugs used in chemotherapy, such as carfilzomib and dexamethasone, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving MDM2 Inhibitor KRT-232, lenalidomide, carfilzomib, and dexamethasone together may work better in treating patients with multiple myeloma. |
>Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
Clinical Trial Conditions for DEXACEN-4
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Clinical Trial Locations for DEXACEN-4
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Clinical Trial Progress for DEXACEN-4
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Clinical Trial Sponsors for DEXACEN-4
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