CLINICAL TRIALS PROFILE FOR DEZOCINE
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All Clinical Trials for DEZOCINE
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT02673723 ↗ | The Application of Docozine Combined With Sufentanil for Awake Tracheal Intubation | Completed | The First Affiliated Hospital of Anhui Medical University | Phase 4 | 2016-03-01 | Mortality associated with difficult airway in anesthesia is up to 30%. So, it is urgent to find a safe and effective method for intubation. Awake tracheal intubation which is used to retain spontaneous breathing is one of the important measures to ensure the safety of the patients with difficult airway in anesthesia. Sufentanil is used to provide good analgesia and can effectively inhibit the reaction of awake tracheal intubation, however, the outstanding problem is serious respiratory depression after intravenous sufentanil injection. Few study showed that dezocine is a kappa opioid antagonist related to mild respiratory depression and can prevents sufentanil-induced cough during general anesthesia induction.It is necessary to carry out large-scale, multi-center, randomized, controlled clinical study to determine whether dezocine prevents sufentanil-induced respiratory depression and whether dezocine combined sufentanil is a safe and effective method for awake tracheal intubation. |
| NCT02768168 ↗ | The Effects of Dezocine Pretreatment on Dexamethasone Induced Perineal Irritation | Completed | General Hospital of Ningxia Medical University | N/A | 2016-05-01 | The purpose of this study is to investigate the efficacy of dezocine pretreatment on dexamethasone 21-phosphate induced perineal irritation (include pian and pruritus). |
| NCT03147066 ↗ | Dezocine for Prevention of Catheter-related Bladder Discomfort | Completed | Jian-jun Yang | Phase 4 | 2017-09-01 | This study evaluates the efficacy of dezocine in preventing the catheter-related bladder discomfort (CRBD) in a postanesthesia care unit (PACU). |
| NCT04906317 ↗ | The Effectiveness of Sedation and Analgesia in Colonoscopy Treatment of Colorectal Polyps | Recruiting | Sixth Affiliated Hospital, Sun Yat-sen University | N/A | 2020-12-01 | This study aims to evaluate the effectiveness of sedation and analgesia in the treament of colorectal polyps by colonoscopy. |
| NCT04921046 ↗ | Effect of Pretreatment of Lignocaine Versus Midazolam in Prevention of Etomidate Induced Myoclonus. | Completed | Rawalpindi Medical College | Phase 4 | 2015-01-01 | This study is a randomized control trial and it was conducted to compare the effectiveness of pretreatment with lignocaine versus midazolam on the frequency of myoclonus associated with etomidate induction. This was conducted in Holy Family Hospital Rawalpindi in a period of 6 months. |
| NCT05205720 ↗ | Application of Celiac Plexus Block in Postoperative Analgesia of Upper Abdominal Surgery | Not yet recruiting | Health Commission of Zhejiang Province, China | Phase 4 | 2022-01-01 | This subject intends to explore the value of intraoperative celiac plexus block in postoperative acute pain management and its promoting effect on patients' rapid recovery during epigastric laparotomy through a randomized controlled trial. |
| NCT05205720 ↗ | Application of Celiac Plexus Block in Postoperative Analgesia of Upper Abdominal Surgery | Not yet recruiting | Second Affiliated Hospital, School of Medicine, Zhejiang University | Phase 4 | 2022-01-01 | This subject intends to explore the value of intraoperative celiac plexus block in postoperative acute pain management and its promoting effect on patients' rapid recovery during epigastric laparotomy through a randomized controlled trial. |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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