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Last Updated: November 22, 2024

CLINICAL TRIALS PROFILE FOR DOCEFREZ


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All Clinical Trials for DOCEFREZ

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00075374 ↗ Two Regimens of Docetaxel in Treating Patients Who Have Not Received Chemotherapy For Unresectable Stage IIIB or Stage IV Non-Small Cell Lung Cancer Completed National Cancer Institute (NCI) Phase 2 2003-10-01 RATIONALE: Drugs used in chemotherapy, such as docetaxel, use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known which docetaxel regimen is more effective for non-small cell lung cancer. PURPOSE: Randomized phase II trial to compare the effectiveness of two regimens of docetaxel in treating patients who have not previously received chemotherapy for unresectable stage IIIB or stage IV non-small cell lung cancer.
NCT00075374 ↗ Two Regimens of Docetaxel in Treating Patients Who Have Not Received Chemotherapy For Unresectable Stage IIIB or Stage IV Non-Small Cell Lung Cancer Completed Case Comprehensive Cancer Center Phase 2 2003-10-01 RATIONALE: Drugs used in chemotherapy, such as docetaxel, use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known which docetaxel regimen is more effective for non-small cell lung cancer. PURPOSE: Randomized phase II trial to compare the effectiveness of two regimens of docetaxel in treating patients who have not previously received chemotherapy for unresectable stage IIIB or stage IV non-small cell lung cancer.
NCT00260611 ↗ Study of Oxaliplatin and Taxotere in Prostate Cancer Completed Sanofi Phase 2 2004-11-01 The primary objective for this study is to evaluate PSA response rates (response will be defined as a > 50% reduction in PSA levels) in men who have failed primary chemotherapy. The secondary objectives are to compare progression free survival, disease free survival, overall survival, and toxicity (tolerance/safety).
NCT00260611 ↗ Study of Oxaliplatin and Taxotere in Prostate Cancer Completed University of Pittsburgh Phase 2 2004-11-01 The primary objective for this study is to evaluate PSA response rates (response will be defined as a > 50% reduction in PSA levels) in men who have failed primary chemotherapy. The secondary objectives are to compare progression free survival, disease free survival, overall survival, and toxicity (tolerance/safety).
NCT00911820 ↗ Cisplatin, Irinotecan and Bevacizumab (PCA) Versus Docetaxel, Cisplatin, Irinotecan and Bevacizumab (TPCA) in Metastatic Esophageal and Gastric Cancer Active, not recruiting Genentech, Inc. Phase 2 2009-07-01 There is no clear standard of care for metastatic stomach or esophageal cancer in the United States. The purpose of this research study is to determine the differences between two regimens of chemotherapy; Arm A: PCA (Cisplatin, Irinotecan and Bevacizumab) and Arm B: TPCA (Docetaxel, Cisplatin, Irinotecan and Bevacizumab). Docetaxel, Cisplatin, and Irinotecan are traditional chemotherapy drugs. Bevacizumab is an antibody (a protein that attacks a foreign substance in the body). Bevacizumab is believed to stop the formation of new blood vessels that carry nutrients to tumors. Both of the chemotherapy regimens (PCA and TPCA) have been studied in patients with esophageal and gastric cancer, and we are trying to determine if one regimen will keep your cancer from growing and improve how long you can live.
NCT00911820 ↗ Cisplatin, Irinotecan and Bevacizumab (PCA) Versus Docetaxel, Cisplatin, Irinotecan and Bevacizumab (TPCA) in Metastatic Esophageal and Gastric Cancer Active, not recruiting Massachusetts General Hospital Phase 2 2009-07-01 There is no clear standard of care for metastatic stomach or esophageal cancer in the United States. The purpose of this research study is to determine the differences between two regimens of chemotherapy; Arm A: PCA (Cisplatin, Irinotecan and Bevacizumab) and Arm B: TPCA (Docetaxel, Cisplatin, Irinotecan and Bevacizumab). Docetaxel, Cisplatin, and Irinotecan are traditional chemotherapy drugs. Bevacizumab is an antibody (a protein that attacks a foreign substance in the body). Bevacizumab is believed to stop the formation of new blood vessels that carry nutrients to tumors. Both of the chemotherapy regimens (PCA and TPCA) have been studied in patients with esophageal and gastric cancer, and we are trying to determine if one regimen will keep your cancer from growing and improve how long you can live.
NCT00911820 ↗ Cisplatin, Irinotecan and Bevacizumab (PCA) Versus Docetaxel, Cisplatin, Irinotecan and Bevacizumab (TPCA) in Metastatic Esophageal and Gastric Cancer Active, not recruiting SCRI Development Innovations, LLC Phase 2 2009-07-01 There is no clear standard of care for metastatic stomach or esophageal cancer in the United States. The purpose of this research study is to determine the differences between two regimens of chemotherapy; Arm A: PCA (Cisplatin, Irinotecan and Bevacizumab) and Arm B: TPCA (Docetaxel, Cisplatin, Irinotecan and Bevacizumab). Docetaxel, Cisplatin, and Irinotecan are traditional chemotherapy drugs. Bevacizumab is an antibody (a protein that attacks a foreign substance in the body). Bevacizumab is believed to stop the formation of new blood vessels that carry nutrients to tumors. Both of the chemotherapy regimens (PCA and TPCA) have been studied in patients with esophageal and gastric cancer, and we are trying to determine if one regimen will keep your cancer from growing and improve how long you can live.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for DOCEFREZ

Condition Name

Condition Name for DOCEFREZ
Intervention Trials
Prostate Cancer 4
Gastric Cancer 2
Non Small Cell Lung Cancer 2
Lung Cancer 2
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Condition MeSH

Condition MeSH for DOCEFREZ
Intervention Trials
Prostatic Neoplasms 5
Carcinoma, Non-Small-Cell Lung 4
Carcinoma 4
Squamous Cell Carcinoma of Head and Neck 3
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Clinical Trial Locations for DOCEFREZ

Trials by Country

Trials by Country for DOCEFREZ
Location Trials
United States 50
France 4
Taiwan 3
Israel 2
United Kingdom 2
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Trials by US State

Trials by US State for DOCEFREZ
Location Trials
Texas 7
Massachusetts 4
Pennsylvania 4
Florida 4
California 4
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Clinical Trial Progress for DOCEFREZ

Clinical Trial Phase

Clinical Trial Phase for DOCEFREZ
Clinical Trial Phase Trials
Phase 3 1
Phase 2 9
Phase 1/Phase 2 2
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Clinical Trial Status

Clinical Trial Status for DOCEFREZ
Clinical Trial Phase Trials
Recruiting 3
Terminated 3
Withdrawn 3
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Clinical Trial Sponsors for DOCEFREZ

Sponsor Name

Sponsor Name for DOCEFREZ
Sponsor Trials
Dana-Farber Cancer Institute 3
The University of Texas Health Science Center, Houston 2
Janssen Pharmaceuticals 1
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Sponsor Type

Sponsor Type for DOCEFREZ
Sponsor Trials
Industry 12
Other 11
NIH 1
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