CLINICAL TRIALS PROFILE FOR DOLOPHINE HYDROCHLORIDE
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All Clinical Trials for DOLOPHINE HYDROCHLORIDE
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT00149630 ↗ | Pharmacogenetics of Disulfiram for Cocaine | Completed | National Institute on Drug Abuse (NIDA) | Phase 2 | 2005-01-01 | Previous research has shown that disulfiram, a medication sometimes used for treating alcoholism, discourages cocaine use among cocaine addicts who are undergoing methadone treatment. By blocking the enzyme dopamine beta hydroxylase (DBH), disulfiram increases levels of dopamine and produces an unpleasant sense of hyperstimulation and discomfort in cocaine users. This study will evaluate the effectiveness of disulfiram in preventing drug relapse among cocaine and opiate addicts with varying inherited levels of DBH. |
| NCT00149630 ↗ | Pharmacogenetics of Disulfiram for Cocaine | Completed | Yale University | Phase 2 | 2005-01-01 | Previous research has shown that disulfiram, a medication sometimes used for treating alcoholism, discourages cocaine use among cocaine addicts who are undergoing methadone treatment. By blocking the enzyme dopamine beta hydroxylase (DBH), disulfiram increases levels of dopamine and produces an unpleasant sense of hyperstimulation and discomfort in cocaine users. This study will evaluate the effectiveness of disulfiram in preventing drug relapse among cocaine and opiate addicts with varying inherited levels of DBH. |
| NCT00149630 ↗ | Pharmacogenetics of Disulfiram for Cocaine | Completed | Baylor College of Medicine | Phase 2 | 2005-01-01 | Previous research has shown that disulfiram, a medication sometimes used for treating alcoholism, discourages cocaine use among cocaine addicts who are undergoing methadone treatment. By blocking the enzyme dopamine beta hydroxylase (DBH), disulfiram increases levels of dopamine and produces an unpleasant sense of hyperstimulation and discomfort in cocaine users. This study will evaluate the effectiveness of disulfiram in preventing drug relapse among cocaine and opiate addicts with varying inherited levels of DBH. |
| NCT00726830 ↗ | Methadone, Morphine, or Oxycodone in Treating Pain in Patients With Cancer | Terminated | National Cancer Institute (NCI) | N/A | 2009-03-01 | RATIONALE: Methadone, morphine, or oxycodone may help relieve pain caused by cancer. It is not yet known whether methadone is more effective than morphine or oxycodone in treating pain in patients with cancer. PURPOSE: This randomized clinical trial is studying methadone to see how well it works compared with morphine or oxycodone in treating pain in patients with cancer. |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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