You're using a free limited version of DrugPatentWatch: Upgrade for Complete Access

Last Updated: November 2, 2024

CLINICAL TRIALS PROFILE FOR ELIGLUSTAT TARTRATE


✉ Email this page to a colleague

« Back to Dashboard


All Clinical Trials for ELIGLUSTAT TARTRATE

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00358150 ↗ A Study of the Efficacy and Safety of Eliglustat Tartrate (Genz-112638) in Type 1 Gaucher Patients Completed Genzyme, a Sanofi Company Phase 2 2006-06-01 Gaucher disease is a genetic disease that results in a deficiency of an enzyme acid beta-glucosidase, also known as glucocerebrosidase. This enzyme is needed to digest a substrate (lipid) called glucosylceramide and, to a lesser degree, glucosylsphingosine. In participants with Gaucher disease, the liver, spleen, bone marrow and brain show increases in lipid concentration, specifically in cells derived from the monocyte/macrophage system. Eliglustat tartrate (Genz-112638) is an oral drug that may regulate the Gaucher disease process by decreasing the synthesis of glucosylceramide. The primary objective of this study is to evaluate the efficacy, safety and pharmacokinetics (PK) of eliglustat tartrate, administered as an oral dose of either 50 milligram (mg) twice daily (BID) or 100 mg BID, to men and women with Gaucher disease Type 1 for 52 weeks.
NCT00891202 ↗ A Study of Eliglustat Tartrate (Genz-112638) in Patients With Gaucher Disease (ENGAGE) Completed Genzyme, a Sanofi Company Phase 3 2009-11-01 This Phase 3 study was designed to confirm the efficacy and safety of eliglustat tartrate (Genz-112638) in participants with Gaucher disease Type 1.
NCT00943111 ↗ A Study of Eliglustat Tartrate (Genz-112638) in Patients With Gaucher Disease Who Have Reached Therapeutic Goals With Enzyme Replacement Therapy (ENCORE) Completed Genzyme, a Sanofi Company Phase 3 2009-09-01 This Phase 3 study was designed to confirm the efficacy and safety of eliglustat tartrate (Genz-112638) in participants with Gaucher disease type 1 who had reached therapeutic goals with enzyme replacement therapy (ERT).
NCT01074944 ↗ A Study of Eliglustat Tartrate (Genz-112638) in Patients With Gaucher Disease to Evaluate Once Daily Versus Twice Daily Dosing (EDGE) Completed Genzyme, a Sanofi Company Phase 3 2010-06-01 The primary objective of this study was to evaluate the efficacy and safety of once daily (QD) versus twice daily (BID) dosing of eliglustat tartrate (Genz-112638) in participants with Gaucher disease type 1 who had demonstrated clinical stability on BID dosing of eliglustat tartrate (Genz-112638). The secondary objective was to evaluate the pharmacokinetics (PK) of Genz-99067 when eliglustat tartrate (Genz-112638) was administered QD and BID in participants with Gaucher disease type 1 who had demonstrated clinical stability on BID dosing of eliglustat tartrate (Genz-112638).
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for ELIGLUSTAT TARTRATE

Condition Name

Condition Name for ELIGLUSTAT TARTRATE
Intervention Trials
Gaucher Disease 3
Gaucher Disease, Type 1 3
Cerebroside Lipidosis Syndrome 1
Gaucher Disease, Non-Neuronopathic Form 1
[disabled in preview] 0
This preview shows a limited data set
Subscribe for full access, or try a Trial

Condition MeSH

Condition MeSH for ELIGLUSTAT TARTRATE
Intervention Trials
Gaucher Disease 6
Deficiency Diseases 1
Renal Insufficiency 1
Lipidoses 1
[disabled in preview] 0
This preview shows a limited data set
Subscribe for full access, or try a Trial

Clinical Trial Locations for ELIGLUSTAT TARTRATE

Trials by Country

Trials by Country for ELIGLUSTAT TARTRATE
Location Trials
United States 35
Russian Federation 4
Canada 3
Serbia 2
Argentina 2
This preview shows a limited data set
Subscribe for full access, or try a Trial

Trials by US State

Trials by US State for ELIGLUSTAT TARTRATE
Location Trials
New York 4
Virginia 3
Georgia 3
Connecticut 3
California 3
This preview shows a limited data set
Subscribe for full access, or try a Trial

Clinical Trial Progress for ELIGLUSTAT TARTRATE

Clinical Trial Phase

Clinical Trial Phase for ELIGLUSTAT TARTRATE
Clinical Trial Phase Trials
Phase 3 3
Phase 2 1
Phase 1 2
[disabled in preview] 0
This preview shows a limited data set
Subscribe for full access, or try a Trial

Clinical Trial Status

Clinical Trial Status for ELIGLUSTAT TARTRATE
Clinical Trial Phase Trials
Completed 6
[disabled in preview] 0
This preview shows a limited data set
Subscribe for full access, or try a Trial

Clinical Trial Sponsors for ELIGLUSTAT TARTRATE

Sponsor Name

Sponsor Name for ELIGLUSTAT TARTRATE
Sponsor Trials
Genzyme, a Sanofi Company 5
Sanofi 1
[disabled in preview] 0
This preview shows a limited data set
Subscribe for full access, or try a Trial

Sponsor Type

Sponsor Type for ELIGLUSTAT TARTRATE
Sponsor Trials
Industry 6
[disabled in preview] 0
This preview shows a limited data set
Subscribe for full access, or try a Trial

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.