Study of a New Anti-HIV Drug, T-20, in HIV-Infected Children
Completed
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Phase 1
1969-12-31
The purpose of this study is to determine the best dose of T-20, a new anti-HIV drug, to
treat HIV-infected children.
T-20, unlike other anti-HIV medications, lessens the ability of HIV to infect certain cells
(T cells) in the body. Doctors hope to better treat HIV by adding T-20 to anti-HIV drug
combinations that include 1 or 2 nucleoside reverse transcriptase inhibitors (NRTIs) plus a
nonnucleoside reverse transcriptase inhibitor (NNRTI) and/or a protease inhibitor (PI).
Study of a New Anti-HIV Drug, T-20, in HIV-Infected Children
Completed
National Institute of Allergy and Infectious Diseases (NIAID)
Phase 1
1969-12-31
The purpose of this study is to determine the best dose of T-20, a new anti-HIV drug, to
treat HIV-infected children.
T-20, unlike other anti-HIV medications, lessens the ability of HIV to infect certain cells
(T cells) in the body. Doctors hope to better treat HIV by adding T-20 to anti-HIV drug
combinations that include 1 or 2 nucleoside reverse transcriptase inhibitors (NRTIs) plus a
nonnucleoside reverse transcriptase inhibitor (NNRTI) and/or a protease inhibitor (PI).
A Study to Compare Three Doses of T-20 When Given in Combination With Abacavir, Amprenavir, Ritonavir, and Efavirenz to HIV-Infected Adults
Completed
Trimeris
Phase 2
1999-05-01
The purpose of this study is to see if it is safe and effective to give T-20, a new type of
anti-HIV drug, with a combination of other anti-HIV drugs. The other anti-HIV drugs used are
abacavir (ABC), amprenavir (APV), ritonavir (RTV), and efavirenz (EFV). Three different doses
of T-20 are tested.
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