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Last Updated: November 2, 2024

CLINICAL TRIALS PROFILE FOR FLUNISOLIDE


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All Clinical Trials for FLUNISOLIDE

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00000577 ↗ Asthma Clinical Research Network (ACRN) Withdrawn National Heart, Lung, and Blood Institute (NHLBI) Phase 3 1993-09-01 This study will establish a network of interactive asthma clinical research groups to evaluate current therapies, new therapies, and management strategies for adult asthma.
NCT00000577 ↗ Asthma Clinical Research Network (ACRN) Withdrawn Milton S. Hershey Medical Center Phase 3 1993-09-01 This study will establish a network of interactive asthma clinical research groups to evaluate current therapies, new therapies, and management strategies for adult asthma.
NCT00203684 ↗ Mentored Patient-Oriented Research Career Development Award Unknown status University of California, Los Angeles Phase 1/Phase 2 1969-12-31 Asthmatics have inflammation in the large airways (tubes through which air travels in and out of the lungs). The large airways are located in the central lung. New research shows that asthmatics also have inflammation in the small airways. The small airways are located in the peripheral lung (the parts of the lung away from the central lung). Until now, most of the inhaled medications available have been made up of big particles that never reach the peripheral lung. The purpose of this study is to try to measure the level of inflammation in the peripheral lung in asthmatics and see if this inflammation can be decreased with different types of inhaled corticosteroids. The investigators will check airway inflammation before and after use of an inhaled corticosteroid that has a large particle size and should only reach the large airways (Flunisolide-CFC), and before and after use of an inhaled, small particle corticosteroid that should reach both the large and small airways (Flunisolide-HFA). Subjects will make 6 study visits over two phases of the study. In the first phase, the investigators will collect baseline information about subjects while they are using placebo (inactive substance). In the second phase, subjects will take either the large or small particle corticosteroid. Visits will involve questionnaires and various tests measuring lung function (such as spirometry, forced oscillation, and methacholine challenge). Exhaled nitric oxide will be measured as an indication of inflammation. Subjects will also measure and make note of lung function at home twice daily using a peak expiratory flow meter. Two of the visits will involve fiberoptic bronchoscopy so that the investigators may collect cells and tissue samples without surgery. Another two of the visits will involve the use of high resolution computed tomography (HRCT) scans to indirectly evaluate disease in distant parts of the lungs.
NCT00346775 ↗ Validation Of Preference Module Of Experience With Allergic Rhinitis Nasal Sprays Questionnaire (EARNS-Q) Completed GlaxoSmithKline Phase 3 2006-05-01 The Protocol section needs to be updated using the following text "The main goal of the study was to validate the Preference Module of the EARNS-Q and to test the reliability using Treatment Satisfaction Questionnaire for Medicines (TSQM), a validated questionnaire for determining satisfaction among different treatment. The EARNS-Q is divided into 2 modules, an Experience Module and a Preference Module. The Experience Module includes 28 items, fourteen attribute rating items followed by fourteen importance weighing questions. The Preference Module includes the same items along with preference questions related to each item as well as a global preference question.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for FLUNISOLIDE

Condition Name

Condition Name for FLUNISOLIDE
Intervention Trials
Asthma 3
Childhood Asthma 1
Distal Lung Inflammation 1
Lung Diseases 1
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Condition MeSH

Condition MeSH for FLUNISOLIDE
Intervention Trials
Asthma 2
Pneumonia 1
Inflammation 1
Pulmonary Disease, Chronic Obstructive 1
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Clinical Trial Locations for FLUNISOLIDE

Trials by Country

Trials by Country for FLUNISOLIDE
Location Trials
United States 9
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Trials by US State

Trials by US State for FLUNISOLIDE
Location Trials
California 3
Kentucky 1
Wisconsin 1
North Carolina 1
Missouri 1
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Clinical Trial Progress for FLUNISOLIDE

Clinical Trial Phase

Clinical Trial Phase for FLUNISOLIDE
Clinical Trial Phase Trials
Phase 3 2
Phase 1/Phase 2 1
N/A 1
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Clinical Trial Status

Clinical Trial Status for FLUNISOLIDE
Clinical Trial Phase Trials
Completed 2
Unknown status 1
Withdrawn 1
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Clinical Trial Sponsors for FLUNISOLIDE

Sponsor Name

Sponsor Name for FLUNISOLIDE
Sponsor Trials
National Heart, Lung, and Blood Institute (NHLBI) 2
University of Louisville 1
Milton S. Hershey Medical Center 1
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Sponsor Type

Sponsor Type for FLUNISOLIDE
Sponsor Trials
Other 3
Industry 2
NIH 2
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