Exenatide and Metformin Therapy in Overweight Women With PCOS
Completed
Amylin Pharmaceuticals, LLC.
Phase 2
2006-06-01
Current research has shown that the use of diabetes management practices aimed at reducing
insulin resistance and hyperinsulinemia (such as weight reduction and the administration of
oral antidiabetic drugs) in women with PCOS can not only improve glucose and lipid metabolism
but can also reverse testosterone abnormalities and restore menstrual cycles. A new medicine
called exenatide (Byetta) has been found to reduce body weight, as well as, improve abnormal
glucose metabolism in diabetics. This randomized study will compare Exenatide (Byetta) to
extended release metformin (Fortamet) to combination therapy (both Byetta and Fortamet) on
menstrual cyclicity, hormone profiles and metabolic profiles over a 24-week period in women
with PCOS.
Exenatide and Metformin Therapy in Overweight Women With PCOS
Completed
Metabolic Center of Louisiana Research Foundation
Phase 2
2006-06-01
Current research has shown that the use of diabetes management practices aimed at reducing
insulin resistance and hyperinsulinemia (such as weight reduction and the administration of
oral antidiabetic drugs) in women with PCOS can not only improve glucose and lipid metabolism
but can also reverse testosterone abnormalities and restore menstrual cycles. A new medicine
called exenatide (Byetta) has been found to reduce body weight, as well as, improve abnormal
glucose metabolism in diabetics. This randomized study will compare Exenatide (Byetta) to
extended release metformin (Fortamet) to combination therapy (both Byetta and Fortamet) on
menstrual cyclicity, hormone profiles and metabolic profiles over a 24-week period in women
with PCOS.
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors.
Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data.
The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free.
thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user.
Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.
Alerts Available With Subscription
Alerts are available for users with active subscriptions.