Studies of the Ocular Complications of AIDS (SOCA)--Cytomegalovirus Retinitis Retreatment Trial (CRRT)
Completed
Baylor College of Medicine
Phase 3
1992-12-01
To compare the relative merits of three therapeutic regimens in patients with AIDS and CMV
retinitis who have been previously treated but whose retinitis either is nonresponsive or has
relapsed. These three therapeutic regimens were (1) foscarnet, (2) high-dose ganciclovir, and
(3) combination foscarnet and ganciclovir.
To compare two treatment strategies in patients with relapsed or nonresponsive CMV retinitis:
(1) continuing the same anti-CMV drug or (2) switching to the alternate drug.
Studies of the Ocular Complications of AIDS (SOCA)--Cytomegalovirus Retinitis Retreatment Trial (CRRT)
Completed
Icahn School of Medicine at Mount Sinai
Phase 3
1992-12-01
To compare the relative merits of three therapeutic regimens in patients with AIDS and CMV
retinitis who have been previously treated but whose retinitis either is nonresponsive or has
relapsed. These three therapeutic regimens were (1) foscarnet, (2) high-dose ganciclovir, and
(3) combination foscarnet and ganciclovir.
To compare two treatment strategies in patients with relapsed or nonresponsive CMV retinitis:
(1) continuing the same anti-CMV drug or (2) switching to the alternate drug.
Studies of the Ocular Complications of AIDS (SOCA)--Cytomegalovirus Retinitis Retreatment Trial (CRRT)
Completed
Johns Hopkins University
Phase 3
1992-12-01
To compare the relative merits of three therapeutic regimens in patients with AIDS and CMV
retinitis who have been previously treated but whose retinitis either is nonresponsive or has
relapsed. These three therapeutic regimens were (1) foscarnet, (2) high-dose ganciclovir, and
(3) combination foscarnet and ganciclovir.
To compare two treatment strategies in patients with relapsed or nonresponsive CMV retinitis:
(1) continuing the same anti-CMV drug or (2) switching to the alternate drug.
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