RATIONALE: Antiemetic drugs may help to reduce or prevent nausea and vomiting in patients
treated with chemotherapy. It is not known whether receiving dexamethasone with granisetron
is more effective than receiving dexamethasone with metoclopramide for reducing the side
effects of chemotherapy.
PURPOSE: Randomized phase III trial to compare the effectiveness of dexamethasone with either
granisetron or metoclopramide in patients treated with chemotherapy.
Lerisetron Compared With Granisetron in Preventing Nausea and Vomiting in Men Being Treated With Radiation Therapy for Stage I Seminoma
Unknown status
Simbec Research
Phase 3
1969-12-31
RATIONALE: Antiemetic drugs may help to reduce or prevent nausea and vomiting in patients
treated with radiation therapy. It is not yet known whether lerisetron is more effective than
granisetron in preventing nausea and vomiting.
PURPOSE: Randomized phase III trial to compare the effectiveness of lerisetron with that of
granisetron in preventing nausea and vomiting in men who are being treated with radiation
therapy for stage I seminoma.
Granisetron to Prevent Nausea and Vomiting After Chemotherapy in Patients With Malignant Disease
Unknown status
National Cancer Institute (NCI)
Phase 3
1969-12-31
RATIONALE: Antiemetic drugs such as granisetron may help to prevent nausea and vomiting in
patients treated with chemotherapy.
PURPOSE: Randomized phase III trial to compare the effectiveness of granisetron with that of
a placebo in preventing nausea and vomiting after chemotherapy in patients who have malignant
disease.
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